CAS 223777-15-9

1-[(2R,3S,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl]pyrimidine-2,4-dione

Description:

The chemical substance known as 1-[(2R,3S,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl]pyrimidine-2,4-dione, with the CAS number 223777-15-9, is a complex organic compound characterized by its pyrimidine and tetrahydrofuran moieties. This compound features multiple functional groups, including hydroxyl (-OH) and methoxy (-OCH3) groups, which contribute to its solubility and reactivity. The stereochemistry indicated by the (2R,3S,4S,5R) configuration suggests specific spatial arrangements that can influence its biological activity and interactions. The presence of the pyrimidine ring, a common structure in nucleic acids and pharmaceuticals, suggests potential applications in medicinal chemistry, possibly as an antiviral or anticancer agent. Additionally, the tetrahydrofuran ring provides a cyclic ether structure that may enhance the compound's stability and solubility in organic solvents. Overall, this substance's unique structural features and functional groups make it a subject of interest for further research in various chemical and biological applications.

Formula: C₁₂H₁₈N₂O₇

InChI: InChI=1/C12H18N2O7/c1-19-4-5-20-10-9(17)7(6-15)21-11(10)14-3-2-8(16)13-12(14)18/h2-3,7,9-11,15,17H,4-6H2,1H3,(H,13,16,18)/t7-,9+,10+,11-/m1/s1

Synonyms:

• 2'-O-(2-methoxyethyl)-Uridine

2'-O-(2-Methoxyethyl)uridine

CAS: 223777-15-9

Formula: C₁₂H₁₈N₂O₇

Purity: 97%

Color and Shape: Solid

Molecular weight: 302.2805

Ref: IN-DA00C2NQ

1-((2R,3R,4R,5R)-4-Hydroxy-5-(Hydroxymethyl)-3-(2-Methoxyethoxy)Tetrahydrofuran-2-Yl)Pyrimidine-2,4(1H,3H)-Dione

CAS: 223777-15-9

1-((2R,3R,4R,5R)-4-Hydroxy-5-(Hydroxymethyl)-3-(2-Methoxyethoxy)Tetrahydrofuran-2-Yl)Pyrimidine-2,4(1H,3H)-Dione

Purity: 99%

Molecular weight: 302.28g/mol

Ref: 54-OR1008880

2''-O-(2-Methoxyethyl)uridine

CAS: 223777-15-9

Ref: 7W-GN1355

2'-O-(2-Methoxyethy)uridine

CAS: 223777-15-9

2'-O-(2-Methoxyethy)uridine is a Nucleoside Derivative - 2'-Modified nucleoside.

Formula: C₁₂H₁₈N₂O₇

Color and Shape: Solid

Molecular weight: 302.28

Ref: TM-TNU0309

2'-O-(2-Methoxyethyl)uridine

CAS: 223777-15-9

2'-O-(2-Methoxyethyl)uridine is a nucleoside analog that inhibits the synthesis of DNA, RNA and protein. It can be used as an antimetabolite to treat cancer and prevents tumor growth by interfering with cell division. 2'-O-(2-Methoxyethyl)uridine is often used in combination with other chemotherapeutic drugs. This drug is not active against bacteria and does not inhibit the growth of bacteria. The major disadvantage of this drug is its lack of efficacy against tumors, which may be due to the lack of penetration through the cell membrane or damage to DNA caused by radiation, abiotic factors, or malfunctioning enzymes. 2'-O-(2-Methoxyethyl)uridine has been shown to cause damage to cells by altering their metabolism and affecting the function of their mitochondria. Damage can cause cells to die through apoptosis or necrosis.

Formula: C₁₂H₁₈N₂O₇

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 302.28 g/mol

Ref: 3D-NM16314

1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 223777-15-9

Purity: 97%

Molecular weight: 302.2829895

Ref: 10-F869318