CAS 2238-90-6: psychosine

Description: Psychosine, with the CAS number 2238-90-6, is a sphingolipid that is primarily known for its role in the central nervous system. It is a derivative of sphingosine and is characterized by the presence of a hydroxyl group at the C1 position and a fatty acid chain. Psychosine is particularly significant in the context of certain neurodegenerative diseases, such as Krabbe disease, where its accumulation can lead to toxic effects on oligodendrocytes, the cells responsible for myelinating neurons. This compound is a white to off-white solid at room temperature and is soluble in organic solvents. Its biological activity is linked to various cellular processes, including apoptosis and inflammation. Psychosine's structure allows it to interact with cellular membranes and influence signaling pathways, making it a subject of interest in neurobiology and pathology. Understanding its properties and effects is crucial for developing therapeutic strategies for diseases associated with sphingolipid metabolism.

Formula: C₂₄H₄₇NO₇

InChI: InChI=1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21-,22-,23+,24+/m0/s1

InChI key: InChIKey=HHJTWTPUPVQKNA-PIIMIWFASA-N

SMILES: OCC1OC(OCC(N)C(O)C=CCCCCCCCCCCCCC)C(O)C(O)C1O

Synonyms:

• (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-<span class="text-smallcaps">D</span>-galactopyranoside
• (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl beta-D-galactopyranoside
• (4E)-2-amino-3-hydroxyoctadec-4-en-1-yl beta-D-galactopyranoside
• Galactopyranoside, 2-amino-3-hydroxy-4-octadecenyl
• Galactopyranoside, 2-amino-3-hydroxy-4-octadecenyl, (E)-<span class="text-smallcaps">DL</smallcap>-erythro-β-<smallcap>D</span>-
• Galactosylsphingosine
• Sphingosine galactoside
• beta-D-Galactopyranoside, 2-amino-3-hydroxy-4-octadecenyl, (R-(R*,S*-(E)))-
• erythro-Psychosine
• β-<span class="text-smallcaps">D</span>-Galactopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl
• β-<span class="text-smallcaps">D</span>-Galactopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl
• β-<span class="text-smallcaps">D</span>-Galactopyranoside, 2-amino-3-hydroxy-4-octadecenyl, [R-[R*,S*-(E)]]-

PSYCHOSINE

CAS: 2238-90-6

• Formula: C₂₄H₄₇NO₇
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 461.6325

Psychosine

CAS: 2238-90-6

Psychosine (Galactosylsphingosine) is a PKC inhibitor, and is highly cytotoxic, inducing cell death in a …

• Formula: C₂₄H₄₇NO₇
• Purity: 98%
• Color and Shape: White Powder
• Molecular weight: 461.63

Psychosine (synthetic)

CAS: 2238-90-6

• Formula: C24H47NO7
• Purity: >99%
• Color and Shape: Solid
• Molecular weight: 461.63

Psychosine (free amine)

CAS: 2238-90-6

• Formula: C24H47NO7
• Purity: >99%
• Color and Shape: Solid
• Molecular weight: 461.63

b-D-Galactosylsphingosine - Synthetic

CAS: 2238-90-6

Krabbe disease marker

• Formula: C₂₄H₄₇NO₇
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 461.63 g/mol