CAS 2241014-82-2

NAMPT inhibitor-linker 2

CAS: 2241014-82-2

ADC-4, a c-Kit targeting ADC, includes NAMPT inhibitor-linker 2 and exhibits <7 pM and 40 pM IC50 against GIST-T1 and NCI-H526.

Formula: C₃₄H₃₃FN₆O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 624.66

Ref: TM-T18478

Nampt inhibitor-linker 2

CAS: 2241014-82-2

Nampt inhibitor-linker 2 is a peptide with the amino acid sequence of D-Phe-D-Ala-Lys-Gly-Arg. It is a competitive inhibitor of nicotinamide phosphoribosyltransferase (Nampt), which converts nicotinamide to NAD+ and plays an important role in the production of NAD+. This inhibitor is used as a research tool for studying protein interactions, activators, and receptors. This peptide has been shown to be a ligand for G protein coupled receptor (GPCR) β2 subtype. These receptors are involved in cell signaling pathways that regulate many physiological processes such as glucose metabolism and lipid synthesis. Nampt inhibitor-linker 2 is also known by CAS No. 2241014-82-2.

Formula: C₃₄H₃₃FN₆O₅

Purity: Min. 95%

Molecular weight: 624.7 g/mol

Ref: 3D-RPD01482