CAS 22415-44-7
:2-Methoxy-17α-ethynylestradiol
Description:
2-Methoxy-17α-ethynylestradiol is a synthetic estrogen and a derivative of estradiol, primarily used in hormonal contraceptives and hormone replacement therapies. This compound features a methoxy group at the second carbon position and an ethynyl group at the 17α position, which enhances its oral bioavailability and potency compared to natural estrogens. It exhibits strong estrogenic activity by binding to estrogen receptors, influencing various physiological processes such as the menstrual cycle and reproductive system regulation. The compound is characterized by its lipophilicity, allowing it to easily cross cell membranes and exert its effects. Additionally, it has a relatively long half-life, which contributes to its effectiveness in therapeutic applications. Due to its hormonal activity, 2-Methoxy-17α-ethynylestradiol is subject to regulatory scrutiny, and its use is associated with potential side effects, including thromboembolic events and hormonal imbalances. As with all synthetic hormones, careful consideration of dosage and individual patient factors is essential in its application.
Formula:C21H26O3
InChI:InChI=1/C21H26O3/c1-4-21(23)10-8-17-15-6-5-13-11-18(22)19(24-3)12-16(13)14(15)7-9-20(17,21)2/h1,11-12,14-15,17,22-23H,5-10H2,2-3H3/t14-,15+,17-,20-,21-/m0/s1
InChI key:InChIKey=NRGDXTWZJCEVEB-PVHGPHFFSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=C(OC)C4)(CC1)[H])[H])(CC[C@]2(C#C)O)[H]
Synonyms:- (17α)-2-Methoxy-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol
- 17α-Ethynyl-2-methoxyestradiol
- 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol, 2-methoxy-
- 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, 2-methoxy-, (17alpha)-
- 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, 2-methoxy-, (17α)-
- 2-Methoxy-17α-ethynylestradiol
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Found 3 products.
2-Methoxy-17α-ethynyl Estradiol
CAS:Controlled Product<p>Applications 2-Methoxy-17α-ethynyl Estradiol is a metabolite of the potent synthetic estrogen 17α-Ethynylestradiol (E685100).<br>References Maggs, J.L. et al.: Xenobiotica, 13, 421 (1983); Maggs, J.L. et al.: Biochem. Pharmacol., 32, 2793 (1983); Abdel-Aziz, M.T. et al.: Steroids, 15, 695 (1970);<br></p>Formula:C21H26O3Color and Shape:NeatMolecular weight:326.43
