CAS 2242-98-0

6α-Hydroxycortisol

Description:

6α-Hydroxycortisol is a steroid hormone and a metabolite of cortisol, classified under the glucocorticoids. It is characterized by the presence of a hydroxyl group at the 6α position of the steroid nucleus, which influences its biological activity and solubility. This compound plays a role in the metabolism of cortisol and is involved in various physiological processes, including the regulation of inflammation and immune response. 6α-Hydroxycortisol is typically found in the adrenal cortex and can be measured in biological fluids, serving as a biomarker for adrenal function and stress response. Its chemical structure contributes to its interaction with glucocorticoid receptors, although it is generally less potent than cortisol itself. The substance is of interest in clinical research, particularly in studies related to adrenal disorders and stress-related conditions. As with many steroid hormones, it is important to handle 6α-Hydroxycortisol with care, considering its potential effects on biological systems.

Formula: C₂₁H₃₀O₆

InChI: InChI=1S/C21H30O6/c1-19-5-3-11(23)7-14(19)15(24)8-12-13-4-6-21(27,17(26)10-22)20(13,2)9-16(25)18(12)19/h7,12-13,15-16,18,22,24-25,27H,3-6,8-10H2,1-2H3/t12-,13-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key: InChIKey=GNFTWPCIRXSCQF-HVIRSNARSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](O)C3)=CC(=O)CC4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]

Synonyms:

• (6Alpha,11Beta)-6,11,17,21-Tetrahydroxypregn-4-Ene-3,20-Dione
• (6Alpha,11Beta,17Alpha)-6,11,17,21-Tetrahydroxypregn-4-Ene-3,20-Dione
• (6α,11β)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione
• 6α,11β,17,21-Tetrahydroxypregn-4-ene-3,20-dione
• Corticosterone, 6α,17-dihydroxy-
• NSC 79099
• Pregn-4-ene-3,20-dione, 6,11,17,21-tetrahydroxy-, (6α,11β)-
• Pregn-4-ene-3,20-dione, 6α,11β,17,21-tetrahydroxy-
• 6α-Hydroxycortisol

6α-Hydroxycortisol

CAS: 2242-98-0

Formula: C₂₁H₃₀O₆

Color and Shape: Solid

Molecular weight: 378.4593

Ref: IN-DA00C2UY

6-α-Hydroxy Hydrocortisone

CAS: 2242-98-0

Formula: C₂₁H₃₀O₆

Molecular weight: 378.47

Ref: 4Z-H-103134

6α-Hydroxyhydrocortisone

Controlled Product

CAS: 2242-98-0

Formula: C₂₁H₃₀O₆

Color and Shape: Neat

Molecular weight: 378.46

Ref: 86-MM0185.13

6a-Hydroxy cortisol

Controlled Product

CAS: 2242-98-0

Cortisol is a steroid hormone that is produced in the human body by the adrenal gland. It regulates many metabolic processes, including the breakdown of carbohydrates and proteins. In addition to its role as a hormone, cortisol has important anti-inflammatory properties. Cortisol levels are typically highest in the morning, with levels gradually decreasing throughout the day. Levels of cortisol can also be measured in blood, urine, or amniotic fluid. These measurements can be used to diagnose certain diseases or conditions such as Cushing's syndrome and Addison's disease.

Formula: C₂₁H₃₀O₆

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 378.46 g/mol

Ref: 3D-FH23956

6α-Hydroxy Cortisol-d4

Controlled Product

CAS: 2242-98-0

Applications A labelled metabolite of Cortisol.
References Abel, S., et al. J. Steroid Biochem. Mol. Biol., 45, 445 (1993), Yates, C., et al.: Pharm. Res., 20, 1794 (2003),

Formula: C₂₁H₂₆D₄O₆

Color and Shape: Neat

Molecular weight: 382.48

Ref: TR-H922312

6α-Hydroxy Cortisol

CAS: 2242-98-0

Formula: C₂₁H₃₀O₆

Molecular weight: 378.5

Ref: ST-EA-CP-H9082