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CAS 22423-26-3

:

2,2'-Anhydro-1-beta-arabinofuranosylthymine

Description:
2,2'-Anhydro-1-beta-arabinofuranosylthymine, with the CAS number 22423-26-3, is a nucleoside analog that features a unique structural modification of thymine. This compound is characterized by the presence of an anhydro sugar moiety, which contributes to its stability and potential biological activity. The beta-arabinofuranosyl configuration indicates that the sugar component is in the beta anomeric form, which can influence its interaction with nucleic acid structures. This compound is of interest in medicinal chemistry and virology due to its potential antiviral properties, particularly against certain viruses by mimicking natural nucleosides. Its structural modifications may enhance its resistance to enzymatic degradation, making it a candidate for further research in therapeutic applications. Additionally, the presence of the anhydro linkage may affect its binding affinity to nucleic acid targets, which is crucial for its efficacy as a therapeutic agent. Overall, 2,2'-Anhydro-1-beta-arabinofuranosylthymine represents a significant area of study in the development of antiviral drugs and nucleoside analogs.
Formula:C10H12N2O5
Synonyms:
  • 2,2'-Anhydro-11-beta-D-arabinofuranosylthymine
  • 6H-Furo(2',3':4,5)oxazolo(3,2-A)pyrimidin-6-one, 2,3,3A,9A-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-, (2R-(2alpha,3beta,3abeta,9abeta))-
  • (2R-(2alpha,3beta,3abeta,9abeta))-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-6H-furo(2',3':4,5)oxazolo(3,2-a)pyrimidin-6-one
  • (2R,3R,3aS,9aR)-3-hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
  • 2,2'-Anhydro-5-methyluridine
  • 2,2'-Anhydro-thymidine
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