CAS 22431-46-5

(2R)-N-[2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-methylsulfinyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride

Description:

The chemical substance known as (2R)-N-[2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-methylsulfinyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride, with the CAS number 22431-46-5, is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a pyrrolidine ring, which contributes to its cyclic structure, and includes a carboxamide functional group that enhances its solubility and reactivity. The presence of a chloro substituent and a sulfinyl group indicates potential biological activity, possibly influencing its pharmacological properties. The multiple hydroxyl groups suggest that the compound may engage in hydrogen bonding, affecting its interactions with biological targets. This compound is likely to be soluble in polar solvents due to its hydrophilic characteristics. Its specific stereochemistry may play a crucial role in its biological activity, making it of interest in medicinal chemistry and drug development. Overall, this compound's unique structure and functional groups position it as a candidate for further investigation in therapeutic applications.

Formula: C₁₈H₃₄Cl₂N₂O₆S

InChI: InChI=1/C18H33ClN2O6S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(27-16)28(4)26;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9?,10?,11-,12?,13-,14-,15?,16?,18-,28?;/m1./s1

SMILES: CCCC1C[C@H](C(=NC(C(C)Cl)C2[C@@H]([C@H](C([C@H](O2)S(=O)C)O)O)O)O)N(C)C1.Cl

Clindamycin Sulfoxide

CAS: 22431-46-5

Clindamycin sulfoxide, an active clindamycin metabolite formed by CYP3A4, inhibits P. prevotti, B. fragilis, C. sordelli with MICs 2, 2, 1 mg/L.

Formula: C₁₈H₃₃ClN₂O₆S

Color and Shape: Solid

Molecular weight: 440.98

Ref: TM-T35730

Clindamycin Sulfoxide-13C-d3 (Mixture of Diastereomers)

CAS: 22431-46-5

Formula: C₁₇₁₃CH₃₀D₃ClN₂O₆S

Molecular weight: 444.99

Ref: 4Z-C-5012

Clindamycin Sulfoxide

CAS: 22431-46-5

Formula: C₁₈H₃₃ClN₂O₆S

Color and Shape: White To Off-White Solid

Molecular weight: 440.98

Ref: 4Z-C-502

Clindamycin Sulfoxide

CAS: 22431-46-5

Formula: C₁₈H₃₃ClN₂O₆S

Molecular weight: 440.98

Ref: ST-EA-CP-C26013

Clindamycin Sulfoxide (Mixture of Diastereomers)

Controlled Product

CAS: 22431-46-5

Formula: C₁₈H₃₃ClN₂O₆S

Color and Shape: White

Molecular weight: 440.98

Ref: TR-C580010

Clindamycin-13C,D3 Sulfoxide

Controlled Product

CAS: 22431-46-5

Formula: C₁₇CH₃₀D₃ClN₂O₆S

Color and Shape: Neat

Molecular weight: 444.99

Ref: TR-C580012

Clindamycin sulfoxide

CAS: 22431-46-5

Clindamycin sulfoxide is a potent metabolite of the lincosamide antibiotic clindamycin, which is derived from the fermentation product of *Streptomyces lincolnensis*. This compound acts by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, thereby interfering with the translocation steps in protein elongation. The mechanism effectively suppresses the growth of a broad range of Gram-positive bacteria, including *Staphylococcus aureus*, *Streptococcus pneumoniae*, and anaerobic microorganisms.

Formula: C₁₈H₃₃ClN₂O₆S

Purity: Min. 95%

Molecular weight: 440.98 g/mol

Ref: 3D-AC20486