CAS 22432-95-7

1,3,5-Triazin-2(1H)-one,4-amino-1-(2-deoxy-a-D-erythro-pentofuranosyl)-

Description:

1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-a-D-erythro-pentofuranosyl)-, commonly referred to as a nucleoside analog, is characterized by its triazine ring structure, which is a six-membered heterocycle containing three nitrogen atoms. This compound features an amino group at the 4-position and a deoxyribose sugar moiety, which is essential for its biological activity, particularly in nucleic acid synthesis and function. The presence of the deoxyribose sugar suggests that it may play a role in the inhibition of viral replication or act as an antiviral agent. The compound's structure allows for hydrogen bonding and interactions with nucleic acid targets, making it a potential candidate for therapeutic applications. Its CAS number, 22432-95-7, facilitates its identification in chemical databases. Overall, this compound's unique structural features contribute to its significance in medicinal chemistry and biochemistry, particularly in the development of antiviral drugs.

Formula: C₈H₁₂N₄O₄

Synonyms:

• s-Triazin-2(1H)-one,4-amino-1-(2-deoxy-a-D-erythro-pentofuranosyl)- (8CI)
• 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine
• Nsc 127717
• a-Decitabine

Decitabine Related Compound E (4-Amino-1-(2-deoxy-α-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one)

CAS: 22432-95-7

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₈H₁₂N₄O₄

Color and Shape: White Powder

Molecular weight: 228.08585

Ref: 45-1165259

α-Decitabine

CAS: 22432-95-7

Formula: C₈H₁₂N₄O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 228.2053

Ref: IN-DA00C2DF

4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one

CAS: 22432-95-7

4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one

Purity: 98%

Molecular weight: 228.21g/mol

Ref: 54-OR1067883

Decitabine USP Related Compound E (α-Decitabine)

CAS: 22432-95-7

Formula: C₈H₁₂N₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 228.21

Ref: 4Z-D-772

Decitabine USP Related Compound E

CAS: 22432-95-7

Formula: C₈H₁₂N₄O₄

Molecular weight: 228.2

Ref: ST-EA-CP-D12010

α-Decitabine

Controlled Product

CAS: 22432-95-7

Applications α-Decitabine is shown to inhibit DNA methylation resulting in an effective anticancer agent.
References Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);

Formula: C₈H₁₂N₄O₄

Color and Shape: Neat

Molecular weight: 228.21

Ref: TR-D226730

Decitabine Diacetate

Controlled Product

CAS: 22432-95-7

Applications Decitabine Diacetate is an impurity of Decitabine(D226730). Decitabine inhibits DNA methylation resulting in an effective anticancer agent.
References Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);

Formula: C₁₂H₁₆N₄O₆

Color and Shape: Neat

Molecular weight: 312.279

Ref: TR-D226735

1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine

CAS: 22432-95-7

1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine is a DNA methylation inhibitor that is used to treat cancer. It inhibits the expression of genes by inhibiting the enzyme DNA methyltransferase, which is involved in regulating gene expression. 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine has been shown to be effective against squamous cell carcinoma cells and has significant cytotoxicity against these cancer cells. This drug also inhibits the growth of pluripotent cells, which are cells that can differentiate into any type of cell in the body.

Formula: C₈H₁₂N₄O₄

Purity: Min. 95%

Molecular weight: 228.21 g/mol

Ref: 3D-ID74826