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CAS 2244702-64-3

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  • TGase2-IN-1
    Targetmol
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    TGase2-IN-1

    CAS:
    TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.
    Formula:C23H25N3O3
    Color and Shape:Solid
    Molecular weight:391.46

    Ref: TM-T201596