SOS1 activator 2, identified by its CAS number 2245237-54-9, is a small molecule that functions as a selective activator of the SOS1 protein, which plays a crucial role in the RAS signaling pathway. This compound is primarily studied for its potential therapeutic applications in cancer treatment, particularly in tumors driven by RAS mutations. The characteristics of SOS1 activator 2 include its ability to enhance the exchange of GDP for GTP on RAS proteins, thereby promoting their active form and influencing downstream signaling pathways. It is typically characterized by its molecular structure, which includes specific functional groups that facilitate its interaction with the SOS1 protein. The compound's solubility, stability, and bioavailability are also important factors that influence its efficacy in biological systems. Research into SOS1 activator 2 continues to explore its pharmacological properties, potential side effects, and overall impact on cancer cell proliferation and survival.

SOS1 activator 2

2245237-54-9: SOS1 activator 2, identified by its CAS number 2245237-54-9, is a small molecule that functions as a selective activator of the SOS1 protein, which plays a crucial role in the RAS signaling pathway. This compound is primarily studied for its potential therapeutic applications in cancer treatment, particularly in tumors driven by RAS mutations. The characteristics of SOS1 activator 2 include its ability to enhance the exchange of GDP for GTP on RAS proteins, thereby promoting their active form and influencing downstream signaling pathways. It is typically characterized by its molecular structure, which includes specific functional groups that facilitate its interaction with the SOS1 protein. The compound's solubility, stability, and bioavailability are also important factors that influence its efficacy in biological systems. Research into SOS1 activator 2 continues to explore its pharmacological properties, potential side effects, and overall impact on cancer cell proliferation and survival.

<p>SOS1 activator 2 (Compound 65) is a benzothiazole derivative and an activator of SOS1. It demonstrates a high binding affinity for SOS1, with a Kd of 9 nM. By modulating the Ras-ERK signaling pathway, SOS1 activator 2 is suitable for tumor research.</p>

CAS 2245237-54-9

SOS1 activator 2

SOS1 activator 2

Ref: TM-T204838