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CAS 2245237-61-8

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  • SOS1 agonist-1
    Targetmol
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    SOS1 agonist-1

    CAS:
    <p>SOS1 agonist-1 (compound 79) serves as an agonist for the Son of sevenless homologue 1 (SOS1), a crucial guanine nucleotide exchange factor involved in catalyzing the GDP to GTP exchange on RAS proteins, thus regulating RAS activation. By increasing nucleotide exchange on RAS, SOS1 agonists enhance cellular RAS-GTP levels and induce biphasic signaling alterations in ERK1/2 phosphorylation, playing a pivotal role in anti-cancer activity [1].</p>
    Formula:C26H29BrClFN4O2
    Color and Shape:Solid
    Molecular weight:563.89

    Ref: TM-T84791