CAS 22465-48-1

Acetatocobalamin

Description:

Acetatocobalamin, also known as vitamin B12 acetate, is a derivative of cobalamin, which is essential for various biological functions in the human body. It is characterized by its cobalt-containing corrin ring structure, which is central to its activity as a cofactor in enzymatic reactions, particularly in DNA synthesis and red blood cell formation. Acetatocobalamin is typically a red crystalline powder, reflecting the characteristic color of vitamin B12 compounds. It is soluble in water and exhibits stability under normal conditions, although it can be sensitive to light and heat. This compound plays a crucial role in the metabolism of fatty acids and amino acids, and its deficiency can lead to serious health issues, including anemia and neurological disorders. Acetatocobalamin is often used in dietary supplements and fortified foods to prevent or treat vitamin B12 deficiency. Its bioavailability and effectiveness in the body make it an important compound in nutritional science and medicine.

Formula: C₆₄H₉₁CoN₁₃O₁₆P

InChI: InChI=1S/C62H90N13O14P.C2H4O2.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2(3)4;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3,(H,3,4);/q;;+3/p-3

InChI key: InChIKey=KPFAAKYTRSSOQN-UHFFFAOYSA-K

SMILES: [O-](C(C)=O)[Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O

Synonyms:

• Acetatocobalamin
• Co(Acetato-kappaO)cobinamide dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobalamin, acetato-
• Cobalamin, acetato- (6CI)
• Cobinamide, Co(acetato-kappaO)-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
• Cobinamide, Co-(acetato-κO)-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole, inner salt
• Depo-gamma
• Fresmin S
• Hydroxocobalamine acetate
• Hydroxycobalamine acetate
• Novidroxin
• Twelvmin
• Unii-S535M27N3Q
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, acetate phosphate, 3′-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole, inner salt

Hydroxocobalamin Acetate

CAS: 22465-48-1

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purity: >90.0%(HPLC)

Color and Shape: Orange to Brown to Dark red powder to crystal

Molecular weight: 1,388.41

Ref: 3B-H1542

Hydroxocobalamin Acetate

CAS: 22465-48-1

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Color and Shape: Dark Red Powder

Molecular weight: 1387.57763

Ref: 45-1324308

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate treats B12 deficiency and cyanide poisoning; FDA-approved with few side effects.

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purity: 96.73% - 99.86%

Color and Shape: Solid

Molecular weight: 1388.39

Ref: TM-T13730

Hydroxocobalamin acetate

CAS: 22465-48-1

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purity: 96.0 - 102.0 %

Color and Shape: Dark red crystalline powder or crystals

Molecular weight: 1388.39

Ref: 7W-GE5819

Hydroxycobalamine Acetate

CAS: 22465-48-1

Hydroxycobalamine Acetate

Purity: 98%

Molecular weight: 1,388.39g/mol

Ref: 54-OR1013546

Hydroxocobalamin Acetate (Vitamin B12 Analog)

CAS: 22465-48-1

Formula: C₆₄H₉₂CoN₁₃O₁₆P

Color and Shape: Dark Red Solid

Molecular weight: 1389.42

Ref: 4Z-V-035001

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate

Purity: ≥95%

Molecular weight: 1388.39g/mol

Ref: 54-BUP14167

Hydroxocobalamin Acetate

CAS: 22465-48-1

Formula: C₆₂H₈₉CoN₁₃O₁₅PC₂H₄O₂

Molecular weight: 1346.38 : 60.05

Ref: ST-EA-CP-H13001

Hydroxocobalamin Acetate

Controlled Product

CAS: 22465-48-1

Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Color and Shape: Dark Red

Molecular weight: 1388.39

Ref: TR-H826800

Hydroxocobalamin acetate

CAS: 22465-48-1

Hydroxocobalamin acetate is a water-soluble form of hydroxocobalamin, a vitamin B12 prodrug. It is an insoluble polymer that dissolves slowly in an acidic environment. Hydroxocobalamin acetate has been shown to inhibit the growth of human carcinoma cells in culture and can be used as a test compound for anticancer drugs. Hydroxocobalamin acetate is also used as a mouth rinse agent to prevent or treat dental cavities. In addition, it can be used to relieve the symptoms of gastroesophageal reflux disease (GERD) by reducing the acidity of gastric contents. This drug has been shown to stimulate vasoactive intestinal polypeptide release from enterochromaffin cells and can be used for the treatment of irritable bowel syndrome (IBS). Hydroxocobalamin acetate is poorly soluble in neutral pH environments and should not be given orally.

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purity: Min. 90 Area-%

Color and Shape: Red Powder

Molecular weight: 1,388.39 g/mol

Ref: 3D-FH23894

Cobinamide, Co-(acetato-kO)-, dihydrogen phosphate (ester), innersalt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)

CAS: 22465-48-1

Formula: C₆₄H₉₁CoN₁₃O₁₆P

Purity: 98%

Color and Shape: Solid

Molecular weight: 1388.3918

Ref: IN-DA00I4FP