CAS 224785-91-5: Vardenafil hydrochloride
Description:Vardenafil hydrochloride is a selective phosphodiesterase type 5 (PDE5) inhibitor primarily used in the treatment of erectile dysfunction. It works by enhancing the effects of nitric oxide, leading to increased blood flow to the penis during sexual stimulation. The substance is characterized by its chemical formula, which includes a piperazine ring and a pyrimidine moiety, contributing to its pharmacological activity. Vardenafil hydrochloride is typically administered orally and is known for its rapid onset of action, with effects lasting several hours. It is often marketed under various brand names and is available in different dosages. The compound is soluble in water and exhibits a moderate to high bioavailability. Common side effects may include headaches, flushing, and nasal congestion, while contraindications include the use of nitrates and certain cardiovascular conditions. As with any medication, it is essential for users to consult healthcare professionals for appropriate guidance and to discuss potential interactions with other medications.
Formula:C23H32N6O4S·ClH
InChI:InChI=1S/C23H32N6O4S.ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H
InChI key:InChIKey=XCMULUAPJXCOHI-UHFFFAOYSA-N
SMILES:Cl.O=C1N=C(NN2C(=NC(=C12)C)CCC)C=3C=C(C=CC3OCC)S(=O)(=O)N4CCN(CC)CC4
- Synonyms:
- 2-[2-Ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one hydrochloride
- 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one dihydrochloride
- Imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-, hydrochloride (1:1)
- Levitra
- Piperazine, 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-, monohydrochloride
- Vardenafil HCl
- Vardenafil hydrochloride