CAS 224789-15-5: Vardenafil dihydrochloride
Description:Vardenafil dihydrochloride is a pharmaceutical compound primarily used for the treatment of erectile dysfunction. It is a selective inhibitor of phosphodiesterase type 5 (PDE5), which enhances erectile function by increasing blood flow to the penis in response to sexual stimulation. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation in oral dosage forms. Vardenafil dihydrochloride has a molecular formula that reflects its complex structure, incorporating various functional groups that contribute to its pharmacological activity. The compound exhibits a relatively rapid onset of action, typically within 30 to 60 minutes after administration, and its effects can last for several hours. As with other PDE5 inhibitors, it is important to consider potential side effects, which may include headaches, flushing, and gastrointestinal disturbances. Additionally, vardenafil should be used with caution in patients taking nitrates or those with certain cardiovascular conditions, as it can lead to significant interactions. Overall, vardenafil dihydrochloride is a well-studied and effective treatment option for erectile dysfunction.
Formula:C23H33ClN6O4S
InChI:InChI=1/C23H32N6O4S.ClH/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H
- Synonyms:
- 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine dihydrochloride
- 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride (1:1)
