CAS 2248003-71-4

1H-1,2,3-Triazole-1-acetamide, N-[4-[[5-fluoro-7-(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-4-(1-methylethyl)-, 4-methylbenzenesulfonate (1:1)

Description:

1H-1,2,3-Triazole-1-acetamide, N-[4-[[5-fluoro-7-(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-4-(1-methylethyl)-, 4-methylbenzenesulfonate (1:1) is a complex organic compound characterized by its triazole and quinazoline moieties, which contribute to its potential biological activity. The presence of the triazole ring suggests possible applications in medicinal chemistry, particularly in the development of antifungal or antibacterial agents, due to the triazole's ability to interact with biological targets. The compound also features a sulfonate group, which can enhance solubility and bioavailability in aqueous environments. The fluorine atom and methoxyethoxy substituent on the quinazoline ring may influence the compound's pharmacokinetic properties, such as lipophilicity and metabolic stability. Overall, this compound's structural complexity and functional groups indicate potential for diverse applications in pharmaceuticals, particularly in targeting specific biological pathways or diseases. However, detailed studies on its efficacy, safety, and mechanism of action would be necessary to fully understand its potential uses.

Formula: C₂₄H₂₆FN₇O₃·C₇H₈O₃S

InChI: InChI=1S/C24H26FN7O3.C7H8O3S/c1-15(2)21-12-32(31-30-21)13-22(33)28-16-4-6-17(7-5-16)29-24-23-19(25)10-18(35-9-8-34-3)11-20(23)26-14-27-24;1-6-2-4-7(5-3-6)11(8,9)10/h4-7,10-12,14-15H,8-9,13H2,1-3H3,(H,28,33)(H,26,27,29);2-5H,1H3,(H,8,9,10)

InChI key: InChIKey=AWHHAHZPRULJMA-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=C(OCCOC)C=C2F)N=CN1)C3=CC=C(NC(CN4C=C(C(C)C)N=N4)=O)C=C3.S(=O)(=O)(O)C1=CC=C(C)C=C1

Synonyms:

• AZD3229 tosylate
• 1H-1,2,3-Triazole-1-acetamide, N-[4-[[5-fluoro-7-(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-4-(1-methylethyl)-, 4-methylbenzenesulfonate (1:1)
• AZD 3229 tosylate
• N-(4-[[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino]phenyl)-2-[4-(propan-2-yl)-1H-[1,2,3]triazol-1-yl]acetamide tosylate
• AZD-3229 tosylate

AZD3229 Tosylate

CAS: 2248003-71-4

AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal

Formula: C₃₁H₃₄FN₇O₆S

Color and Shape: Solid

Molecular weight: 651.71

Ref: TM-T71894

AZD3229 Tosylate

CAS: 2248003-71-4

AZD3229 Tosylate is a small molecule tyrosine kinase inhibitor, which is derived through advanced chemical synthesis methodologies. The compound acts by selectively targeting and inhibiting specific receptor tyrosine kinases, which play a crucial role in the signaling pathways that regulate cellular processes such as proliferation, differentiation, and survival.

Formula: C₃₁H₃₄FN₇O₆S

Purity: Min. 95%

Molecular weight: 651.71 g/mol

Ref: 3D-YPD00371