Mal-PEG5-COOtBu, also known as Maleimide-Polyethylene Glycol (PEG) with a t-butyl ester, is a synthetic compound characterized by its unique structure that combines a maleimide group with a polyethylene glycol (PEG) chain and a t-butyl ester functional group. The maleimide moiety is known for its ability to undergo thiol-ene click reactions, making it useful in bioconjugation and drug delivery applications. The PEG segment imparts hydrophilicity, enhancing solubility in aqueous environments and improving biocompatibility, which is particularly advantageous in pharmaceutical formulations. The t-butyl ester group serves as a protecting group that can be hydrolyzed under specific conditions, allowing for controlled release or activation of the compound. Overall, Mal-PEG5-COOtBu is valued in biomedical research and development for its versatility in modifying biomolecules and facilitating targeted delivery systems. Its properties make it suitable for applications in areas such as tissue engineering, drug delivery, and the development of diagnostic tools.

Mal-PEG5-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Mal-PEG5-COOtBu

2250216-91-0: Mal-PEG5-COOtBu, also known as Maleimide-Polyethylene Glycol (PEG) with a t-butyl ester, is a synthetic compound characterized by its unique structure that combines a maleimide group with a polyethylene glycol (PEG) chain and a t-butyl ester functional group. The maleimide moiety is known for its ability to undergo thiol-ene click reactions, making it useful in bioconjugation and drug delivery applications. The PEG segment imparts hydrophilicity, enhancing solubility in aqueous environments and improving biocompatibility, which is particularly advantageous in pharmaceutical formulations. The t-butyl ester group serves as a protecting group that can be hydrolyzed under specific conditions, allowing for controlled release or activation of the compound. Overall, Mal-PEG5-COOtBu is valued in biomedical research and development for its versatility in modifying biomolecules and facilitating targeted delivery systems. Its properties make it suitable for applications in areas such as tissue engineering, drug delivery, and the development of diagnostic tools.

Mal-PEG5-t-butyl ester

Mal-PEG5-Boc

<p>Mal-PEG5-Boc (Mal-PEG5-COOtBu) is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs.</p>

CAS 2250216-91-0

Mal-PEG5-COOtBu

Mal-PEG5-t-butyl ester

Ref: IN-DA01JOT7

Mal-PEG5-Boc

Ref: 54-BUP06064

Mal-PEG5-Boc

Ref: TM-T18295