CAS 22509-74-6

N-Carbethoxyphthalimide

Description:

N-Carbethoxyphthalimide is an organic compound characterized by its phthalimide structure, which is a bicyclic compound featuring a five-membered imide ring fused to a six-membered aromatic ring. This compound is typically used as a reagent in organic synthesis, particularly in the formation of amines through the process of N-alkylation. It possesses a carbethoxy group, which enhances its reactivity and solubility in organic solvents. N-Carbethoxyphthalimide is known for its stability under standard conditions, making it suitable for various synthetic applications. It is generally a white to off-white crystalline solid, and its melting point and solubility can vary depending on the specific conditions. Safety data indicates that, like many organic compounds, it should be handled with care, using appropriate personal protective equipment to avoid inhalation or skin contact. Overall, N-Carbethoxyphthalimide is a valuable intermediate in the synthesis of pharmaceuticals and other complex organic molecules.

Formula: C₁₁H₉NO₄

InChI: InChI=1S/C11H9NO4/c1-2-16-11(15)12-9(13)7-5-3-4-6-8(7)10(12)14/h3-6H,2H2,1H3

InChI key: InChIKey=VRHAQNTWKSVEEC-UHFFFAOYSA-N

SMILES: C(OCC)(=O)N1C(=O)C=2C(C1=O)=CC=CC2

Synonyms:

• 1,3-Dioxo-1,3-dihydroisoindole-2-carboxylic acid ethyl ester
• 1,3-Dioxoisoindoline-2-carboxylic acid ethyl ester
• 2-(Carbethoxy)phthalimide
• 2-Isoindolinecarboxylic acid, 1,3-dioxo-, ethyl ester
• 2H-Isoindole-2-carboxylic acid, 1,3-dihydro-1,3-dioxo-, ethyl ester
• Carbethoxyphthalimide
• Ethyl 1,3-dioxo-1,3-dihydroisoindole-2-carboxylate
• Ethyl 1,3-dioxo-2,3-dihydro-1H-isoindole-2-carboxylate
• Ethyl 1,3-dioxo-2-isoindolinecarboxylate
• Ethyl 1,3-dioxoisoindoline-2-carboxylate
• Ethyl N-phthaloylcarbamate
• N-(Carboethoxy)phthalimide
• N-(Ethoxycarbonyl)phthalimide
• N-Carboethoxyphthalimide
• N-carbethoxy phthalimide
• NSC 76576
• Nefkens
• Nefkens' reagent
• Reagents, Nefkens'
• ethyl 1,3-dioxo-1,3-dihydro-2H-isoindole-2-carboxylate

N-Ethoxycarbonylphthalimide [for Peptide Synthesis]

CAS: 22509-74-6

Formula: C₁₁H₉NO₄

Purity: >98.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 219.20

Ref: 3B-C0683

N-Carbethoxyphthalimide

CAS: 22509-74-6

Formula: C₁₁H₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 219.1935

Ref: IN-DA003SVI

N-Carbethoxyphthalimide

CAS: 22509-74-6

N-Carbethoxyphthalimide

Purity: 98%

Color and Shape: White Powder

Molecular weight: 219.19g/mol

Ref: 54-OR323267

N-Carbethoxyphthalimide

CAS: 22509-74-6

Formula: C₁₁H₉NO₄

Molecular weight: 219.20

Ref: 7W-GK8011

N-Ethoxycarbonylphthalimide

CAS: 22509-74-6

Formula: C₁₁H₉NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 219.196

Ref: 10-F018669

N-Carbethoxyphthalimide

Controlled Product

CAS: 22509-74-6

Applications N-Carbethoxyphthalimide is used in the synthetic preparation of a novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
References Hua, Z., et al.: J. Med. Chem., 56, 10003 (2013);

Formula: C₁₁H₉NO₄

Color and Shape: Neat

Molecular weight: 219.19

Ref: TR-C176115