CAS 2251130-41-1

N-(2-Chloro-6-fluorobenzyl)-5-(1H-indazol-3-yl)thiophene-3-carboxamide

CAS: 2251130-41-1

N-(2-Chloro-6-fluorobenzyl)-5-(1H-indazol-3-yl)thiophene-3-carboxamide

Purity: 95%

Molecular weight: 385.85g/mol

Ref: 54-PC1007636

XMU-MP-9

CAS: 2251130-41-1

XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.

Formula: C₁₉H₁₃ClFN₃OS

Color and Shape: Solid

Molecular weight: 385.84

Ref: TM-T200189