CAS 22515-18-0

4,4-Difluorocyclohexanone

Description:

4,4-Difluorocyclohexanone is a cyclic ketone characterized by the presence of two fluorine atoms attached to the 4-position of the cyclohexanone ring. This compound typically exhibits a colorless to pale yellow liquid form and has a distinctive odor. Its molecular structure contributes to its unique chemical properties, including a relatively high boiling point compared to non-fluorinated cyclohexanones due to the electronegative fluorine atoms, which can influence intermolecular interactions. 4,4-Difluorocyclohexanone is soluble in organic solvents and may have limited solubility in water. The presence of fluorine atoms can enhance its reactivity in certain chemical reactions, making it a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Additionally, the compound's stability and reactivity can be influenced by the steric and electronic effects of the fluorine substituents. As with many fluorinated compounds, safety precautions should be taken when handling 4,4-difluorocyclohexanone due to potential toxicity and environmental concerns.

Formula: C₆H₈F₂O

InChI: InChI=1S/C6H8F2O/c7-6(8)3-1-5(9)2-4-6/h1-4H2

InChI key: InChIKey=NYYSPVRERVXMLJ-UHFFFAOYSA-N

SMILES: FC1(F)CCC(=O)CC1

Synonyms:

• 4,4-Difluorocyclohexan-1-One
• Cyclohexanone, 4,4-difluoro-
• 4,4-Difluorocyclohexanone

4,4-Difluorocyclohexanone

CAS: 22515-18-0

Formula: C₆H₈F₂O

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 134.13

Ref: 3B-D4516

4,4-Difluorocyclohexanone, 97%

CAS: 22515-18-0

4,4-Difluorocyclohexanone is used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU refer

Formula: C₆H₈F₂O

Purity: 97%

Color and Shape: Colorless to pale cream to cream to yellow, Fused solid

Molecular weight: 134.13

Ref: 02-H26027

4,4-Difluorocyclohexanone

CAS: 22515-18-0

Formula: C₆H₈F₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 134.1239

Ref: IN-DA0033UU

4,4-Difluorocyclohexan-1-one

CAS: 22515-18-0

4,4-Difluorocyclohexan-1-one

Formula: C₆H₈F₂O

Purity: ≥95%

Color and Shape: colourless to off white to faint orange solid

Molecular weight: 134.12g/mol

Ref: 54-PC7922

4,4-Difluorocyclohexan-1-one

CAS: 22515-18-0

4,4-Difluorocyclohexan-1-one (DFCO) is a colorless liquid that is soluble in organic solvents. It has been shown to have potential as a treatment for Alzheimer's disease due to its ability to inhibit the conformational changes in the amyloid beta peptide. DFCO was synthesized by reacting pyridazine with difluoroethanol, which led to the formation of two stereoisomers: R and S. The R stereoisomer was found to be more potent than the S stereoisomer in inhibiting acetylcholine release from human lung cells and had better binding affinity for adenosine receptors. This compound also showed antiinflammatory properties when it was used as an inhibitor of prostaglandin synthesis in mice.

Formula: C₆H₈F₂O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 134.12 g/mol

Ref: 3D-FD104427

4,4-Difluorocyclohexanone

CAS: 22515-18-0

Formula: C₆H₈F₂O

Purity: 97%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 134.126

Ref: 10-F044463