CAS 2252247-80-4

SHIP2-IN-1

Description:

SHIP2-IN-1, identified by its CAS number 2252247-80-4, is a small molecule inhibitor that targets the SHIP2 (SH2 domain-containing inositol 5-phosphatase 2) enzyme. This compound is of interest in biochemical research due to its potential role in modulating signaling pathways associated with various cellular processes, including insulin signaling and cell proliferation. SHIP2 is implicated in several diseases, including metabolic disorders and cancer, making its inhibition a valuable therapeutic strategy. The characteristics of SHIP2-IN-1 include its ability to selectively inhibit SHIP2 activity, which can lead to increased levels of phosphoinositides, thereby influencing downstream signaling cascades. The compound's structure typically features specific functional groups that enhance its binding affinity to the SHIP2 active site. Additionally, SHIP2-IN-1 is often evaluated for its pharmacokinetic properties, such as solubility, stability, and bioavailability, which are crucial for its potential development as a therapeutic agent. Overall, SHIP2-IN-1 represents a promising tool for investigating SHIP2-related biological functions and therapeutic interventions.

Formula: C₁₇H₁₃Cl₂FN₄O

Synonyms:

• SHIP2-IN-1
• Phosphatase,SHIP2IN1,Inhibitor,inhibit,SHIP2 IN 1,SHIP-2-IN-1
• (R)-5-(5-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)pyrimidin-2-amine
• 2-Pyrimidinamine, 5-[5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-

SHIP2-IN-1

CAS: 2252247-80-4

SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 µM),and used in the research of Alzheimer’s disease.

Formula: C₁₇H₁₃Cl₂FN₄O

Purity: 99.02%

Color and Shape: Solid

Molecular weight: 379.22

Ref: TM-T12901

SHIP2-IN-1

CAS: 2252247-80-4

Formula: C₁₇H₁₃Cl₂FN₄O

Purity: 99.72%

Molecular weight: 379.2157

Ref: IN-DA01V6ZT

SHIP2-IN-1

CAS: 2252247-80-4

SHIP2-IN-1

Purity: ≥98%

Molecular weight: 379.22g/mol

Ref: 54-BUP12633