CAS 2252403-56-6: 6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one

Description: 6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one, with CAS number 2252403-56-6, is a synthetic organic compound characterized by its complex structure, which includes multiple functional groups such as fluorine, hydroxyl, and piperazine moieties. This compound exhibits potential pharmacological properties, making it of interest in medicinal chemistry. Its molecular framework suggests it may interact with biological targets, possibly influencing pathways related to various diseases. The presence of fluorine atoms typically enhances lipophilicity and metabolic stability, while the piperazine ring can contribute to receptor binding affinity. Additionally, the compound's stereochemistry, particularly the (2S) configuration, may play a crucial role in its biological activity. Overall, this compound represents a class of molecules that could be explored for therapeutic applications, although specific biological data would be necessary to fully understand its efficacy and safety profile.

Formula: C₃₀H₃₀F₂N₆O₃

InChI: InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1

InChI key: InChIKey=NXQKSXLFSAEQCZ-SFHVURJKSA-N

SMILES: O=C1N=C(C=2C=C(F)C(=NC2N1C=3C(=NC=CC3C)C(C)C)C=4C(F)=CC=CC4O)N5CCN(C(=O)C=C)CC5C

Synonyms:

• Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-
• 6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
• 4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one
• AMG-510 racemate

(S)-AMG-510

CAS: 2252403-56-6

• Purity: 98.57%
• Molecular weight: 560.59g/mol

Sotorasib

CAS: 2252403-56-6

• Formula: C₃₀H₃₀F₂N₆O₃
• Molecular weight: 560.61

(S)-AMG-510

CAS: 2252403-56-6

(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and …

• Formula: C₃₀H₃₀F₂N₆O₃
• Purity: 98.01% - 99.76%
• Color and Shape: Solid
• Molecular weight: 560.59

AMG 510 racemate

CAS: 2252403-56-6

Racemic mixture of AMG 510

• Formula: C₃₀H₃₀F₂N₆O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 560.59 g/mol