CAS 2252403-56-6

6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one

Description:

6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one, with CAS number 2252403-56-6, is a synthetic organic compound characterized by its complex structure, which includes multiple functional groups such as fluorine, hydroxyl, and piperazine moieties. This compound exhibits potential pharmacological properties, making it of interest in medicinal chemistry. Its molecular framework suggests it may interact with biological targets, possibly influencing pathways related to various diseases. The presence of fluorine atoms typically enhances lipophilicity and metabolic stability, while the piperazine ring can contribute to receptor binding affinity. Additionally, the compound's stereochemistry, particularly the (2S) configuration, may play a crucial role in its biological activity. Overall, this compound represents a class of molecules that could be explored for therapeutic applications, although specific biological data would be necessary to fully understand its efficacy and safety profile.

Formula: CHFNO

InChI: InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1

InChI key: InChIKey=NXQKSXLFSAEQCZ-SFHVURJKSA-N

SMILES: O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C

Synonyms:

• Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-
• 6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
• 4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one
• AMG-510 racemate
• Sotorasib
• 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl]-1H,2H-pyrido[2,3-d]pyrimidin-2-one
• AMG-510 atropisomer
• chiral AMG 510, single isomer
• AMG 510
• CPD2809
• AMG-510，AMG510
• Sotorasib (AMG-510)
• AMG 510 USP/EP/BP
• Sotorasib (racemate)
• 6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-1-[4-METHYL-2-(PROPAN-2-YL)PYRIDIN-3-YL]-4-[(2S)-2-METHYL-4-(P

(S)-AMG-510

CAS: 2252403-56-6

(S)-AMG-510

Purity: ≥98%

Molecular weight: 560.59g/mol

Ref: 54-BUP12961

Sotorasib

CAS: 2252403-56-6

Formula: C₃₀H₃₀F₂N₆O₃

Molecular weight: 560.61

Ref: 4Z-S-200001

(S)-AMG-510

CAS: 2252403-56-6

(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.

Formula: C₃₀H₃₀F₂N₆O₃

Purity: 99.05% - 99.76%

Color and Shape: Solid

Molecular weight: 560.594

Ref: TM-T22258

AMG 510 racemate

CAS: 2252403-56-6

Racemic mixture of AMG 510

Formula: C₃₀H₃₀F₂N₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 560.59 g/mol

Ref: 3D-BA172506