CAS 22571-95-5

Symphytine

Description:

Symphytine, with the CAS number 22571-95-5, is an alkaloid derived from the plant Symphytum, commonly known as comfrey. This compound is primarily recognized for its potential therapeutic properties, particularly in traditional medicine, where it has been used for its anti-inflammatory and wound-healing effects. Symphytine is characterized by its complex molecular structure, which includes a bicyclic framework typical of many alkaloids. It exhibits solubility in organic solvents, which is common for many plant-derived compounds. However, its use has raised safety concerns due to potential hepatotoxicity associated with comfrey products, leading to regulatory scrutiny in some regions. As a result, while symphytine may have beneficial applications, its safety profile necessitates careful consideration and further research to fully understand its pharmacological effects and potential risks. Overall, symphytine represents an interesting area of study within phytochemistry and pharmacognosy, highlighting the need for ongoing investigation into the benefits and hazards of natural compounds.

Formula: C₂₀H₃₁NO₆

InChI: InChI=1S/C20H31NO6/c1-6-13(4)18(23)27-16-8-10-21-9-7-15(17(16)21)11-26-19(24)20(25,12(2)3)14(5)22/h6-7,12,14,16-17,22,25H,8-11H2,1-5H3/b13-6+/t14-,16+,17+,20-/m0/s1

InChI key: InChIKey=MVWPTZQHBOWRTF-SMLWLWDZSA-N

SMILES: C(OC([C@](C(C)C)([C@H](C)O)O)=O)C=1[C@]2(N(CC[C@H]2OC(/C(=C/C)/C)=O)CC1)[H]

Synonyms:

• Symphytine
• 2-Butenoic acid, 2-methyl-, (1R,7aR)-7-[[(2S,3S)-2,3-dihydroxy-2-(1-methylethyl)-1-oxobutoxy]methyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, (2E)-
• 2-Butenoic acid, 2-methyl-, 7-[[2,3-dihydroxy-2-(1-methylethyl)-1-oxobutoxy]methyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-yl ester, [1R-[1α(E),7(2S*,3S*),7aβ]]-
• 7-Tiglylretronecine viridiflorate
• 7-Tiglyl-9-viridiflorylretronecine

Symphytine

CAS: 22571-95-5

Symphytine, a natural substance, induces liver tumors by damaging DNA and causing mutations in hepatic cells.

Formula: C₂₀H₃₁NO₆

Color and Shape: Solid

Molecular weight: 381.46

Ref: TM-T34757

Symphytine

CAS: 22571-95-5

Formula: C₂₀H₃₁NO₆

Molecular weight: 381.47

Ref: 4Z-S-229001

Symphytine

CAS: 22571-95-5

Symphytine is an alkaloid compound that is derived from the comfrey plant, scientifically known as Symphytum officinale. This plant is a member of the Boraginaceae family and is native to parts of Europe and Asia. The mode of action of symphytine involves its role in promoting cell proliferation and tissue regeneration, contributed to by its potential to stimulate fibroblast growth and collagen synthesis. However, it is important to note that the compound can also have toxicological effects, particularly due to its pyrrolizidine alkaloid structure, which has been associated with hepatotoxicity under certain conditions.

Formula: C₂₀H₃₁NO₆

Purity: Min. 95%

Molecular weight: 381.5 g/mol

Ref: 3D-XAA57195