CAS: 2259-96-3 - Cyclothiazide

Formula: C₁₄H₁₆ClN₃O₄S₂

InChI: InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)

InChI key: InChIKey=BOCUKUHCLICSIY-UHFFFAOYSA-N

SMILES: O=S(=O)(N)C=1C=C2C(=CC1Cl)NC(NS2(=O)=O)C3CC4C=CC3C4

Synonyms:

• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-, 1,1-dioxide
• 3-[(1S,4S)-bicyclo[2.2.1]hept-5-en-2-yl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
• 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide
• 6-Chloro-3-(5-bicyclo[2.2.1]hept-2-enyl)-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
• 6-Chloro-3-(5-norbornen-2-yl)-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide
• 6-chloro-3,4-dihydro-3-(8,9,10-trinorborn-5-en-2-yl)-2H-1,2,4-benzothiadiazine-7-sulphonamide 1,1-dioxide
• Anhydron
• Aquirel
• Ciclotiazida
• Cyclothiazid
• Doburil
• Fluidil
• Lilly 35483
• MDi 193
• Renazide
• Valmiran

2H-1,2,4-Benzothiadiazine-7-sulfonamide,3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-, 1,1-dioxide

CAS: 2259-96-3

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 389.8775

Cyclothiazide

CAS: 2259-96-3

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Purity: ≥ 95.0%
• Color and Shape: White to off-white or light yellow powder
• Molecular weight: 389.88

Cyclothiazide

CAS: 2259-96-3

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Color and Shape: Neat
• Molecular weight: 389.88

Cyclothiazide

CAS: 2259-96-3

• Color and Shape: Neat

Cyclothiazide (mixture of isomers)

CAS: 2259-96-3

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Purity: >95.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 389.87

Cyclothiazide

CAS: 2259-96-3

Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Purity: 98.23% - 98.74%
• Color and Shape: Crystals From Dilute Alcohol Solid
• Molecular weight: 389.88

Cyclothiazide

CAS: 2259-96-3

M01473 - Cyclothiazide

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Purity: >98%
• Color and Shape: Solid
• Molecular weight: 389.8699951171875

Cyclothiazide

CAS: 2259-96-3

Applications Diuretic; antihypertensive. A subunit-specific inhibitor of GABAC receptors. References Wentling, C.D., et al.: Anal. …

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Color and Shape: White To Grey
• Molecular weight: 389.88

Cyclothiazide

CAS: 2259-96-3

Cyclothiazide is a low potency drug that has been shown to have inhibitory properties in …

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Purity: Min. 95%
• Color and Shape: White To Off-White To Yellow Solid
• Molecular weight: 389.88 g/mol

Cyclothiazide (AS) (DISCONTINUED)

CAS: 2259-96-3

Sulfonamides used as drugs

• Formula: C₁₄H₁₆ClN₃O₄S₂
• Color and Shape: White Off-White Powder
• Molecular weight: 389.88