CAS 22608-11-3

Demethoxycurcumin

Description:

Demethoxycurcumin is a chemical compound derived from curcumin, which is the active component of turmeric. It is characterized by its yellow-orange color and is known for its potential biological activities, including anti-inflammatory, antioxidant, and anticancer properties. The molecular structure of demethoxycurcumin features a diketone moiety, which contributes to its reactivity and biological effects. It is less studied than curcumin but has garnered interest due to its potential therapeutic applications. Demethoxycurcumin is soluble in organic solvents but has limited solubility in water, which can affect its bioavailability. The compound is often investigated in the context of natural product chemistry and pharmacology, with research focusing on its mechanisms of action and potential health benefits. As with many phytochemicals, the stability and efficacy of demethoxycurcumin can be influenced by factors such as pH, temperature, and the presence of other compounds. Overall, demethoxycurcumin represents a promising area of study within the field of medicinal chemistry.

Formula: C₂₀H₁₈O₅

InChI: InChI=1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+

InChI key: InChIKey=HJTVQHVGMGKONQ-LUZURFALSA-N

SMILES: C(=C/C(CC(/C=C/C1=CC=C(O)C=C1)=O)=O)\C2=CC(OC)=C(O)C=C2

Synonyms:

• (1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
• (1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
• (1E,6E)-1-(4-Hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
• 1,6-Heptadiene-3,5-Dione, 1-(4-Hydroxy-3-Methoxyphenyl)-7-(4-Hydroxyphenyl)-
• 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (E,E)-
• 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(p-hydroxyphenyl)-
• 1,6-heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)-
• 1-(4-Hydroxy-3-Methoxyphenyl)-7-(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione
• 1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
• Curcumin II
• Desmethoxycurcumin
• Monodemethoxycurcumin

Demethoxycurcumin

CAS: 22608-11-3

Demethoxycurcumin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₀H₁₈O₅

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 338.36

Ref: 11-4746S

Desmethoxycurcumin

CAS: 22608-11-3

Ketone-phenols and ketones with other oxygen function

Formula: C₂₀H₁₈O₅

Color and Shape: Orange Yellow Powder

Molecular weight: 338.11542

Ref: 45-1173100

Demethoxycurcumin

CAS: 22608-11-3

Formula: C₂₀H₁₈O₅

Purity: ≥ 98.0%

Color and Shape: Yellow to orange powder

Molecular weight: 338.35

Ref: 7W-GL0560

(1E,6E)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione

CAS: 22608-11-3

(1E,6E)-1-(4-Hydroxy-3-Methoxyphenyl)-7-(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione

Purity: 98%

Molecular weight: 338.35g/mol

Ref: 54-OR1007851

Demethoxycurcumin

CAS: 22608-11-3

Demethoxycurcumin

Purity: ≥90%

Molecular weight: 338.35g/mol

Ref: 54-BUP00166

Demethoxycurcumin

CAS: 22608-11-3

Demethoxycurcumin (DMC) is one of the main active compounds of curcuminoids found in turmeric powder, which is used as a spice in Asian cooking and traditional medicine, has anti-inflammation and anti-cancer activities, the mechanism of DMC-mediated anti-invasive activity involves modulation of the expression of invasion-associated proteins, possibly by targeting NF-κB in MDA-MB-231 cells.

Formula: C₂₀H₁₈O₅

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 338.359

Ref: BP-BP0472

Demethoxycurcumin

CAS: 22608-11-3

Color and Shape: Neat

Ref: 04-CA12135000

Demethoxycurcumin

CAS: 22608-11-3

Formula: C₂₀H₁₈O₅

Purity: >98.0%(HPLC)

Color and Shape: Light red to Yellow to Red powder to crystal

Molecular weight: 338.36

Ref: 3B-D6479

Demethoxy Curcumin

CAS: 22608-11-3

Formula: C₂₀H₁₈O₅

Color and Shape: Yellow Solid

Molecular weight: 338.36

Ref: 4Z-C-6921

Demethoxycurcumin

CAS: 22608-11-3

Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.

Formula: C₂₀H₁₈O₅

Purity: 94.54% - 99.86%

Color and Shape: Solid

Molecular weight: 338.35

Ref: TM-T6S1683

Demethoxycurcumin

CAS: 22608-11-3

Ketone phenol

Formula: C₂₀H₁₈O₅

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 338.36

Ref: 5G-89628

(2E)-Demethoxy Curcumin

CAS: 22608-11-3

Applications The demethoxy derivative of Curcumin (C838500) that regulates anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. It attenuates the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ryu, M.J. et al.: Biochem. Biophys. Res. Comm., 377, 1304 (2008); Sandur, S.K. et al.: Carcinogenesis, 28, 1765 (2007); Huang, T. et al.: J. Agric. Food. Chem., 58, 10639 (2010);

Formula: C₂₀H₁₈O₅

Color and Shape: Pink To Red

Molecular weight: 338.35

Ref: TR-D230815

(2E)-Demethoxy Curcumin-d7

Controlled Product

CAS: 22608-11-3

Formula: C₂₀H₁₁D₇O₅

Color and Shape: Neat

Molecular weight: 345.4

Ref: TR-D230817

Demethoxycurcumin

CAS: 22608-11-3

Demethoxycurcumin is a natural bioactive compound, which is a type of curcuminoid. It is derived from the rhizomes of the plant Curcuma longa, commonly known as turmeric, a member of the ginger family. Demethoxycurcumin is one of the primary components contributing to the characteristic yellow color of turmeric.

Formula: C₂₀H₁₈O₅

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 338.35 g/mol

Ref: 3D-FD20982

Demethoxy Curcumin

CAS: 22608-11-3

Formula: C₂₀H₁₈O₅

Molecular weight: 338.36

Ref: ST-EA-CP-C147002

DEMETHOXYCURCUMIN

CAS: 22608-11-3

Formula: C₂₀H₁₈O₅

Color and Shape: Solid

Molecular weight: 338.359g/mol

Ref: IN-DA00BCK3