CAS 2265910-52-7

[4,4′-Bi-9H-xanthene]-10′a,10a-dicarboxylic acid, 5,5′,6,6′,7,7′-hexahydro-1,1′,5,5′,8,8′-hexahydroxy-6,6′-dimethyl-9,9′-dioxo-, 10′a,10a-dimethyl ester, (5R,5′R,6S,6′S,10′aR,10aR)-

Description:

The chemical substance known as [4,4′-Bi-9H-xanthene]-10′a,10a-dicarboxylic acid, 5,5′,6,6′,7,7′-hexahydro-1,1′,5,5′,8,8′-hexahydroxy-6,6′-dimethyl-9,9′-dioxo-, 10′a,10a-dimethyl ester, (5R,5′R,6S,6′S,10′aR,10aR)- is a complex organic compound characterized by its intricate polycyclic structure, which includes multiple functional groups such as carboxylic acids and esters. This compound features a xanthene backbone, which is known for its fluorescent properties, making it potentially useful in various applications, including dyes and sensors. The presence of multiple hydroxyl groups suggests it may exhibit significant solubility in polar solvents and could participate in hydrogen bonding interactions. Additionally, the stereochemistry indicated by the R and S designations implies that the compound has specific spatial arrangements that could influence its reactivity and interaction with biological systems. Overall, this compound's unique structure and functional groups may confer interesting chemical and physical properties, warranting further investigation for potential applications in materials science or medicinal chemistry.

Synonyms:

• [4,4′-Bi-9H-xanthene]-10′a,10a-dicarboxylic acid, 5,5′,6,6′,7,7′-hexahydro-1,1′,5,5′,8,8′-hexahydroxy-6,6′-dimethyl-9,9′-dioxo-, 10′a,10a-dimethyl ester, (5R,5′R,6S,6′S,10′aR,10aR)-

4,4′-Secalonic acid D

CAS: 2265910-52-7

4,4′-Secalonic acid D (Compound 12) is a PARP1 inhibitor. By inhibiting PARP1, 4,4′-Secalonic acid D induces the accumulation of ROS and DNA damage, activating the caspase-3/GSDME pathway, which leads to tumor cell apoptosis (apoptosis) and pyroptosis (pyroptosis). It exhibits antitumor activity.

Formula: C₃₂H₃₀O₁₄

Color and Shape: Solid

Molecular weight: 638.572

Ref: TM-TN9010