CAS 22662-39-1

Rafoxanide

Description:

Rafoxanide is a chemical compound primarily used as an anthelmintic agent, particularly in veterinary medicine for the treatment of parasitic infections in livestock. It belongs to the class of compounds known as salicylanilides and is characterized by its ability to disrupt the energy metabolism of parasites, leading to their death. Rafoxanide is typically administered in the form of a salt, which enhances its solubility and bioavailability. The compound exhibits a broad spectrum of activity against various helminths, making it effective in controlling infections caused by flukes and other parasitic worms. Its mechanism of action involves interference with the mitochondrial function of the parasites, ultimately resulting in their inability to generate ATP. Rafoxanide is generally well-tolerated in animals, but like all pharmaceuticals, it may have side effects and contraindications that need to be considered. Additionally, its use is regulated in many countries to ensure safety and efficacy in animal health.

Formula: C₁₉H₁₁Cl₂I₂NO₃

InChI: InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)

InChI key: InChIKey=NEMNPWINWMHUMR-UHFFFAOYSA-N

SMILES: C(NC1=CC(Cl)=C(OC2=CC=C(Cl)C=C2)C=C1)(=O)C3=C(O)C(I)=CC(I)=C3

Synonyms:

• 3,5-Diiodo-3′-chloro-4′-(p-chlorophenoxy)salicylanilide
• 3,5-Diodo-3′-chloro-4′-(p-chlorophenoxy)salicylanilide
• 3′-Chloro-4′-(4-chlorophenoxy)-3,5-diiodosalicylanilide
• 3′-Chloro-4′-(p-chlorophenoxy)-3,5-diiodosalicylanilide
• Benzamide, N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-
• Disalan
• N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
• N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-benzamide
• NSC 355278
• Ranide
• Salicylanilide, 3′-chloro-4′-(p-chlorophenoxy)-3,5-diiodo-

Rafoxanide

CAS: 22662-39-1

Formula: C₁₉H₁₁Cl₂I₂NO₃

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 626.01

Ref: 3B-R0108

Rafoxanide, Vetranal

CAS: 22662-39-1

Formula: C₁₉H₁₁Cl₂I₂NO₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 626.0105

Ref: IN-DA00ILQR

N-(3-Chloro-4-(4-Chlorophenoxy)Phenyl)-2-Hydroxy-3,5-DIIodobenzamide

CAS: 22662-39-1

N-(3-Chloro-4-(4-Chlorophenoxy)Phenyl)-2-Hydroxy-3,5-DIIodobenzamide

Purity: 99%

Molecular weight: 626.01g/mol

Ref: 54-OR1013979

Rafoxanide

CAS: 22662-39-1

Formula: C₁₉H₁₁Cl₂I₂NO₃

Purity: ≥ 98.0% (dried basis)

Color and Shape: White to off-white, beige, grey or light-brown powder

Molecular weight: 626.01

Ref: 7W-GP7762

Rafoxanide

CAS: 22662-39-1

Rafoxanide

Purity: ≥98%

Molecular weight: 626.01g/mol

Ref: 54-BUP18390

Rafoxanide

Controlled Product

CAS: 22662-39-1

Formula: C₁₉H₁₁Cl₂I₂NO₃

Color and Shape: White

Molecular weight: 626.01

Ref: 04-C16805200

Rafoxanide

Controlled Product

CAS: 22662-39-1

Formula: C₁₉H₁₁Cl₂I₂NO₃

Color and Shape: Neat

Molecular weight: 626.01

Ref: 86-MM0363.00

Rafoxanide

CAS: 22662-39-1

Formula: C₁₉H₁₁Cl₂I₂NO₃

Molecular weight: 626.02

Ref: 4Z-R-691

Rafoxanide

CAS: 22662-39-1

Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.

Formula: C₁₉H₁₁Cl₂I₂NO₃

Purity: 99.47%

Color and Shape: Slight Yellowish Brown Injectable Solution &White Oral Solution

Molecular weight: 626.01

Ref: TM-T7093

Rafoxanide

CAS: 22662-39-1

Applications Rafoxanide is a thyroid hormone receptor.
References Bernal, J., et al.: Vitam. Horm., 71, 95 (2005), Fujimoto, N., et al.: J. Endocrinol., 181, 77 (2005), Hamers, T., et al.: Toxicol. Sci., 92, 157 (2006), Jugan, M., et al.: Biochem. Pharmacol., 79, 939 (2010),

Formula: C₁₉H₁₁Cl₂I₂NO₃

Color and Shape: White

Molecular weight: 626.01

Ref: TR-R073500

Rafoxanide

CAS: 22662-39-1

Anthelmintic; anti-parasitic

Formula: C₁₉H₁₁Cl₂I₂NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 626.01 g/mol

Ref: 3D-FR31088

N-(3-Chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodobenzamide

CAS: 22662-39-1

Purity: 99%

Molecular weight: 626.0100098

Ref: 10-F869027

Rafoxanide

CAS: 22662-39-1

Color and Shape: Neat

Ref: 61-FOR0363.00