CAS 226929-39-1

LB42708

Description:

LB42708, with the CAS number 226929-39-1, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. While specific characteristics such as its molecular formula, structure, and physical properties may vary, compounds like LB42708 are typically evaluated for their biological activity, solubility, stability, and toxicity profiles. It is important to note that compounds in this category are often investigated for their interactions with biological targets, which can include enzymes or receptors, and may exhibit specific pharmacological effects. The development and characterization of such compounds involve rigorous testing and validation to ensure efficacy and safety for potential use in clinical settings. For detailed information regarding its specific characteristics, including its synthesis, mechanism of action, and any clinical data, consulting scientific literature or databases dedicated to chemical substances would be essential.

4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine

CAS: 226929-39-1

Formula: C₃₀H₂₇BrN₄O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 555.4650

Ref: IN-DA0039B1

LB42708

CAS: 226929-39-1

LB42708

Purity: ≥95%

Molecular weight: 555.47g/mol

Ref: 54-BUP03290

LB 42708

Controlled Product

CAS: 226929-39-1

Applications LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors.
References Kim, C., et. al.: Mol. Pharmacol., 78, 142 (2010)

Formula: C₃₀H₂₇BrN₄O₂

Color and Shape: Neat

Molecular weight: 555.46

Ref: TR-L178790

LB42708

CAS: 226929-39-1

LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).

Formula: C₃₀H₂₇BrN₄O₂

Purity: 99.36%

Color and Shape: Solid

Molecular weight: 555.47

Ref: TM-T2678