CAS 22737-96-8

11-cis-Retinol

Description:

11-cis-Retinol, also known as 11-cis-vitamin A, is a vital organic compound that plays a crucial role in vision and biological processes. It is a derivative of vitamin A and is characterized by its specific configuration at the 11th carbon position, which is essential for its function in the visual cycle. This compound is a colorless to pale yellow liquid that is soluble in organic solvents but poorly soluble in water. Its molecular structure features a long hydrocarbon chain with multiple double bonds, contributing to its reactivity and interaction with light. In the retina, 11-cis-Retinol is converted to 11-cis-retinal, which is a key chromophore in the phototransduction pathway, allowing for the conversion of light into electrical signals in photoreceptor cells. Deficiencies in 11-cis-Retinol can lead to vision problems, including night blindness. Additionally, it has implications in various biological processes beyond vision, including cellular growth and differentiation. Proper storage and handling are essential, as it can degrade upon exposure to light and air.

Formula: C₂₀H₃₀O

InChI: InChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6-,12-11+,16-8+,17-13+

InChI key: InChIKey=FPIPGXGPPPQFEQ-IOUUIBBYSA-N

SMILES: C(=C/C(=C/C=C\C(=C\CO)\C)/C)\C=1C(C)(C)CCCC1C

Synonyms:

• 11-cis-Vitamin A alcohol
• 11-cis-Retinol
• Retinol, 11-cis-

11-cis Retinol

CAS: 22737-96-8

11-cisRetinol, a vitamin A isomer, forms from a retinyl ester via RPE65. It's crucial for the visual cycle and cone pigment formation.

Formula: C₂₀H₃₀O

Color and Shape: Solid

Molecular weight: 286.459

Ref: TM-T38220

11-cis-Retinol

CAS: 22737-96-8

Formula: C₂₀H₃₀O

Molecular weight: 286.46

Ref: 4Z-R-7618

11-cis-Retinol, >85%

CAS: 22737-96-8

Stability Light Sensitive, Temperature Sensitive
Applications A metabolite of Vitamin A (R252000(M)).
References Touma, S., et al.: Biochem. Pharmacol., 78, 1127 (2009), Muniz, A., et al.: Biochem., 48, 6854 (2009), Guignard, T., et al.: J. Biol. Chem., 285, 18759 (2010),

Formula: C₂₀H₃₀O

Purity: >85%

Color and Shape: Neat

Molecular weight: 286.45

Ref: TR-R252105

11-cis-Retinol

CAS: 22737-96-8

11-cis-Retinol is a retinoid that has been synthesized in the laboratory. 11-cis-Retinol has been shown to inhibit the activity of bacterial enzymes such as signal peptide, which is involved in protein synthesis. It also inhibits the growth of bacteria by inhibiting energy metabolism and atp-binding cassette transporter. Retinoids are active against infectious diseases, including HIV, and have shown anti-inflammatory properties that may be due to their ability to suppress cytokine production. 11-cis-Retinol is used as a vitamin supplement and is applied topically to treat eye disorders.

Formula: C₂₀H₃₀O

Purity: Min. 85%

Color and Shape: Yellow Powder

Molecular weight: 286.45 g/mol

Ref: 3D-FR163659

11-Cis-Retinol

CAS: 22737-96-8

Formula: C₂₀H₃₀O

Molecular weight: 286.46

Ref: ST-EA-CP-R65008