The chemical substance known as "(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-thieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide," with the CAS number 227609-66-7, is a complex organic compound characterized by its unique thienoquinoline structure. This compound features a thieno[3,2-b]quinoline core, which is a bicyclic system that incorporates both sulfur and nitrogen atoms, contributing to its potential biological activity. The presence of a bromo and a fluoro substituent on the phenyl ring enhances its chemical reactivity and may influence its pharmacological properties. The "1,1-dioxide" designation indicates the presence of two oxygen atoms double-bonded to the sulfur atom, which can affect the compound's solubility and stability. This substance is of interest in medicinal chemistry, particularly for its potential applications in drug development, due to its structural features that may interact with biological targets. Overall, its specific stereochemistry and functional groups suggest a complex interplay of properties that could be explored for therapeutic uses.

(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-thieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide

227609-66-7: The chemical substance known as "(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-thieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide," with the CAS number 227609-66-7, is a complex organic compound characterized by its unique thienoquinoline structure. This compound features a thieno[3,2-b]quinoline core, which is a bicyclic system that incorporates both sulfur and nitrogen atoms, contributing to its potential biological activity. The presence of a bromo and a fluoro substituent on the phenyl ring enhances its chemical reactivity and may influence its pharmacological properties. The "1,1-dioxide" designation indicates the presence of two oxygen atoms double-bonded to the sulfur atom, which can affect the compound's solubility and stability. This substance is of interest in medicinal chemistry, particularly for its potential applications in drug development, due to its structural features that may interact with biological targets. Overall, its specific stereochemistry and functional groups suggest a complex interplay of properties that could be explored for therapeutic uses.

<p>A-278637 is a quinoline derivative that has been shown to be effective in treating acute decompensated heart failure. The mechanism of the drug is not fully understood, but it is thought to inhibit the opening of certain membrane channels in the bladder and detrusor muscle. A-278637 has also been shown to produce a significant increase in systolic pressure, which may be due to its ability to activate cardiac β 1 -adrenergic receptors.</p>

CAS 227609-66-7

(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydro-thieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide

A-278637

Ref: 3D-CJA60966