CAS 22788-18-7

Carboxyphosphamide

Description:

Carboxyphosphamide, with the CAS number 22788-18-7, is a chemical compound that belongs to the class of phosphamide derivatives. It is characterized by the presence of both carboxylic acid and phosphamide functional groups, which contribute to its reactivity and potential applications in various fields. This compound is typically a white to off-white solid and is soluble in polar solvents, reflecting its polar nature due to the functional groups present. Carboxyphosphamide is of interest in medicinal chemistry, particularly for its potential use in pharmaceuticals, as it may exhibit biological activity related to its structural features. The compound's stability and reactivity can be influenced by environmental factors such as pH and temperature. Additionally, it may undergo hydrolysis, leading to the release of phosphoric acid and other byproducts. As with many phosphamide compounds, safety precautions should be taken when handling Carboxyphosphamide due to potential toxicity and reactivity. Overall, its unique chemical structure makes it a subject of interest for further research and application in various chemical and biological contexts.

Formula: C₇H₁₅Cl₂N₂O₄P

InChI: InChI=1S/C7H15Cl2N2O4P/c8-2-4-11(5-3-9)16(10,14)15-6-1-7(12)13/h1-6H2,(H2,10,14)(H,12,13)

InChI key: InChIKey=QLAKAJLYYGOZQL-UHFFFAOYSA-N

SMILES: N(P(OCCC(O)=O)(N)=O)(CCCl)CCCl

Synonyms:

• 3-[[Amino[bis(2-chloroethyl)amino]phosphinyl]oxy]propanoic acid
• Asta 5754
• Carboxycyclophosphamide
• Carboxyphosphamide
• Hydracrylic acid, N,N-bis(2-chloroethyl)phosphorodiamidate
• N,N-Bis(2-chloroethyl)-O-2-carboxyethylphosphorodiamide
• NSC 145124
• O-(2-Carboxyethyl) N,N-bis(2-chloroethyl)phosphorodiamidate
• Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-, ester with hydracrylic acid
• Propanoic Acid, 3-[[Amino[Bis(2-Chloroethyl)Amino]Phosphinyl]Oxy]-

Cyclophosphamide Impurity 25 (Carboxyphosphamide)

CAS: 22788-18-7

Formula: C₇H₁₅Cl₂N₂O₄P

Color and Shape: White To Off-White Solid

Molecular weight: 293.08

Ref: 4Z-C-10219

Carboxyphosphamide

CAS: 22788-18-7

Carboxyphosphamide, an inactive byproduct, forms from cyclophosphamide via aldophosphamide oxidation.

Formula: C₇H₁₅Cl₂N₂O₄P

Color and Shape: Solid

Molecular weight: 293.08

Ref: TM-T37108

Carboxyphosphamide

Controlled Product

CAS: 22788-18-7

Applications A metabolite of Cyclophosphamide (CPA) (C988580).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),

Formula: C₇H₁₅Cl₂N₂O₄P

Color and Shape: Neat

Molecular weight: 293.08

Ref: TR-C181350

Carboxyphosphamide

CAS: 22788-18-7

Formula: C₇H₁₅Cl₂N₂O₄P

Molecular weight: 293.08

Ref: ST-EA-CP-C37038