CAS 227963-15-7

(S)-3-(6-Methoxypyridin-3-yl)-3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoic acid

CAS: 227963-15-7

(S)-3-(6-Methoxypyridin-3-yl)-3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoic acid

Purity: 98%

Molecular weight: 439.52g/mol

Ref: 54-OR1062967

MK-0429

CAS: 227963-15-7

MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).

Formula: C₂₃H₂₉N₅O₄

Color and Shape: Solid

Molecular weight: 439.51

Ref: TM-T16085

MK-0429

CAS: 227963-15-7

Formula: C₂₃H₂₉N₅O₄

Molecular weight: 439.52

Ref: 4Z-K-031121

MK-0429

CAS: 227963-15-7

MK-0429 is an inhibitor of the integrin receptor, which prevents fibrosis and inflammation in the kidneys. It has been shown to be a potent antagonist against fibrinogen and potent inducer of the release of interferon alfa-2b. MK-0429 has also been shown to have potent anti-inflammatory properties and to inhibit the growth of melanoma cells in mice. A phase 1 study was performed on 12 patients to assess safety and pharmacokinetics. The drug was well tolerated, with no significant adverse events observed during the trial.

Formula: C₂₃H₂₉N₅O₄

Purity: Min. 95%

Molecular weight: 439.5 g/mol

Ref: 3D-CJA96315