CAS 2280-32-2
:Kanamycin C
Description:
Kanamycin C is an aminoglycoside antibiotic that is primarily used to treat bacterial infections, particularly those caused by Gram-negative bacteria. It is derived from the bacterium *Micromonospora kanamycetica*. Kanamycin C exhibits a broad spectrum of antibacterial activity and is effective against various pathogens, including some strains of Mycobacterium tuberculosis. The chemical structure of Kanamycin C features multiple amino groups, which contribute to its mechanism of action by inhibiting bacterial protein synthesis. It binds to the 30S ribosomal subunit, leading to misreading of mRNA and ultimately preventing bacterial growth. Kanamycin C is typically administered via injection due to its poor oral bioavailability. While it is effective, its use is associated with potential side effects, including nephrotoxicity and ototoxicity, necessitating careful monitoring of kidney function and hearing in patients receiving treatment. As with other aminoglycosides, resistance can develop, often through enzymatic modification of the drug, underscoring the importance of appropriate use in clinical settings.
Formula:C18H36N4O11
InChI:InChI=1S/C18H36N4O11/c19-4-1-5(20)16(33-18-13(28)8(21)10(25)6(2-23)31-18)14(29)15(4)32-17-9(22)12(27)11(26)7(3-24)30-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12-,13-,14-,15+,16-,17-,18-/m1/s1
InChI key:InChIKey=WZDRWYJKESFZMB-BNWSHAKYSA-N
SMILES:O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](N)[C@H]2O)[C@@H](N)C[C@H]1N)[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N
Synonyms:- <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[3-amino-3-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→6)]-2-deoxy-
- Kanamycin C
- O-2-Amino-2-deoxy-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-O-[3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)]-2-deoxy-<smallcap>D</span>-streptamine
- alpha-D-glucopyranoside, (1R,2S,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2-amino-2-deoxy-
- D-Streptamine, O-2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-2-deoxy-
- O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-2-deoxy-D-streptamine
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Found 3 products.
Kanamycin C
CAS:<p>Inhibitor of protein synthesis; aminoglycoside</p>Formula:C18H36N4O11Purity:Min. 95%Molecular weight:484.5 g/mol
