CAS 22838-58-0

N-Boc-D-valine

Description:

N-Boc-D-valine is a derivative of the amino acid valine, characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group on the nitrogen atom of the amino group. This modification enhances its stability and solubility, making it useful in peptide synthesis and other organic chemistry applications. The compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but less soluble in water. N-Boc-D-valine is often utilized in the synthesis of peptides due to its ability to protect the amine group during coupling reactions, allowing for selective reactions at other functional groups. Its chirality, being a D-amino acid, can influence the biological activity of peptides synthesized from it. Additionally, N-Boc-D-valine is used in various research applications, including drug development and the study of protein structure and function. Proper handling and storage are essential, as with many chemical substances, to ensure safety and maintain its integrity.

Formula: C₁₀H₁₈NO₄

InChI: InChI=1/C10H19NO4/c1-6(2)7(8(12)13)11-9(14)15-10(3,4)5/h6-7H,1-5H3,(H,11,14)(H,12,13)/p-1/t7-/m1/s1

SMILES: CC(C)[C@H](C(=O)[O-])N=C(O)OC(C)(C)C

Synonyms:

• Boc-D-Val-OH
• N-(tert-Butoxycarbonyl)-D-valine
• (2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate
• Boc-D-valine

N-(tert-Butoxycarbonyl)-D-valine

CAS: 22838-58-0

Formula: C₁₀H₁₉NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 217.27

Ref: 3B-B2991

N-Boc-D-valine, 98+%

CAS: 22838-58-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₉NO₄

Purity: 98+%

Color and Shape: White, Powder

Molecular weight: 217.27

Ref: 02-L09193

Boc-D-valine

CAS: 22838-58-0

Formula: C₁₀H₁₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 217.2622

Ref: IN-DA0034JT

Boc-D-Val-OH

CAS: 22838-58-0

Formula: C₁₀H₁₉NO₄

Molecular weight: 217.27

Ref: 7W-GM8730

D-Valine, N-BOC protected

CAS: 22838-58-0

D-Valine, N-BOC protected

Formula: C₁₀H₁₉NO₄

Purity: 99%

Color and Shape: white solid

Molecular weight: 217.26g/mol

Ref: 54-OR51864

Boc-D-Val-OH

CAS: 22838-58-0

Boc-D-Val-OH is a synthetic, cyclic peptide that contains a hydrophobic Boc group. It has been shown to inhibit the uptake of calcium by caco-2 cells in vitro. This peptide also inhibits the growth of cancer cells and may be used as an anticancer agent. Boc-D-Val-OH binds to the membrane of caco-2 cells and blocks the uptake of calcium ions, thus inhibiting cellular functions such as protein synthesis. This compound is stable under a variety of conditions and has potent inhibitory activity against cancer cell proliferation.

Formula: C₁₀H₁₉NO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 217.26 g/mol

Ref: 3D-FB37411

BOC-D-Valine extrapure, 99%

CAS: 22838-58-0

Formula: C₁₀H₁₉NO₄

Purity: min. 99.0%

Color and Shape: White, Crystalline powder

Molecular weight: 217.30

Ref: SR-35049

boc-d-val-oh

CAS: 22838-58-0

Formula: C₁₀H₁₉NO₄

Purity: 97%

Color and Shape: Solid, White crystalline powder

Molecular weight: 217.265

Ref: 10-F045442

tert-Butoxycarbonyl-D-valine

Controlled Product

CAS: 22838-58-0

Applications tert-Butoxycarbonyl-D-valine is used in the preparation of selective CCR1 antagonists in the treatment of rheumatoid arthritis. Also used in the preparation of antileishmanial agents.
References Gardner, D. et al.: Bioorg. Med. Chem. Lett., 23, 3833 (2013); Casanova, E. et al.: ChemMedChem., 8, 1161 (2013);

Formula: C₁₀H₁₉NO₄

Color and Shape: Neat

Molecular weight: 217.26

Ref: TR-B690965

Boc-D-Valine

CAS: 22838-58-0

Formula: C₁₀H₁₉NO₄

Molecular weight: 217.27

Ref: ST-EA-CP-C162026