CAS 2284-20-0

4-Methoxyphenyl isothiocyanate

Description:

4-Methoxyphenyl isothiocyanate, with the CAS number 2284-20-0, is an organic compound characterized by the presence of an isothiocyanate functional group attached to a methoxy-substituted phenyl ring. This compound typically appears as a colorless to pale yellow liquid and has a distinctive, pungent odor. It is soluble in organic solvents such as ethanol and acetone but has limited solubility in water. 4-Methoxyphenyl isothiocyanate is known for its reactivity, particularly in nucleophilic substitution reactions, making it useful in various synthetic applications, including the preparation of other isothiocyanates and in the study of biological activities. It has been investigated for its potential anticancer properties and as a tool in chemical biology due to its ability to modify proteins through thiocyanate formation. As with many isothiocyanates, it is important to handle this compound with care, as it may pose health risks if inhaled or ingested. Proper safety precautions should be taken when working with this substance in a laboratory setting.

Formula: C₈H₇NOS

InChI: InChI=1S/C8H7NOS/c1-10-8-4-2-7(3-5-8)9-6-11/h2-5H,1H3

InChI key: InChIKey=VRPQCVLBOZOYCG-UHFFFAOYSA-N

SMILES: N(=C=S)C1=CC=C(OC)C=C1

Synonyms:

• 1-Isothiocyanato-4-methoxybenzene
• 1-Methoxy-4-isothiocyanatobenzene
• 4-(Isothiocyanato)anisole
• 4-Anisyl isothiocyanate
• 4-Isothiocyanato-1-methoxybenzene
• 4-Isothiocyanatophenyl methyl ether
• 4-Methoxyphenyl Isothiocyanate
• 4-Methoxyphenylisothiocyanate
• Benzene, 1-isothiocyanato-4-methoxy-
• Isothiocyanic acid, p-methoxyphenyl ester
• NSC 77713
• p-Anisyl isothiocyanate

4-Methoxyphenyl Isothiocyanate

CAS: 2284-20-0

Formula: C₈H₇NOS

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Yellow powder to lump to clear liquid

Molecular weight: 165.21

Ref: 3B-I0513

4-Methoxyphenyl isothiocyanate, 98%

CAS: 2284-20-0

4-Methoxyphenyl isothiocyanate has been used in the synthesis of 3-benzyl-2-(4-methoxyphenyl)-3H-[1,2,4]triazolo-[5,1-b]quinazolin-9-one and 2-{[4-amino-3-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-N-arylhydrazinecarbothioamides. This Thermo Scientific Chemicals brand product w

Formula: C₈H₇NOS

Purity: 98%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 165.21

Ref: 02-A15331

4-Methoxyphenyl isothiocyanate

CAS: 2284-20-0

Formula: C₈H₇NOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 165.2123

Ref: IN-DA003LOM

4-Methoxyphenyl isothiocyanate

CAS: 2284-20-0

4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.

Formula: C₈H₇NOS

Color and Shape: Solid

Molecular weight: 165.21

Ref: TM-T203259

4-Methoxyphenyl isothiocyanate

CAS: 2284-20-0

4-Methoxyphenyl isothiocyanate

Formula: C₈H₇NOS

Purity: 98%

Color and Shape: pale yellow liquid

Molecular weight: 165.21g/mol

Ref: 54-OR30146

4-Methoxyphenyl isothiocyanate

CAS: 2284-20-0

Formula: C₈H₇NOS

Purity: 98.0%

Color and Shape: Clear

Molecular weight: 165.21

Ref: 10-F001278