CAS 2285346-31-6

RTS-V5

CAS: 2285346-31-6

RTS-V5 is a protein inhibitor that inhibits the activity of plasminogen activator inhibitor-1 (PAI-1), a protein that prevents fibrinolysis. RTS-V5 binds to PAI-1 and blocks its ability to inhibit the activity of plasminogen activators, which are enzymes that break down blood clots. This inhibition leads to increased levels of the active form of plasminogen activators, which in turn increases the rate of fibrinolysis. RTS-V5 has been shown to be effective against cancer cells in vitro and in animal models by inhibiting growth factor receptors. The mechanism of action for anticancer activity is not fully understood, but it may be due to inhibition of amp-activated protein kinase and/or ubiquitin proteasome system.

Formula: C₂₇H₃₅N₅O₆

Purity: Min. 95%

Molecular weight: 525.6 g/mol

Ref: 3D-KRD34631

RTS-V5

CAS: 2285346-31-6

RTS-V5 is a dual inhibitor of HDAC/proteasome (IC50s: 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively).

Formula: C₂₇H₃₅N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 525.6

Ref: TM-T16805