CAS 22862-76-6: (-)-Anisomycin

Description: (-)-Anisomycin, with the CAS number 22862-76-6, is a naturally occurring antibiotic and a potent inhibitor of protein synthesis. It is derived from the fungus Streptomyces griseolus and is known for its ability to inhibit the peptidyl transferase activity of the ribosome, thereby interfering with the translation process in cells. This compound has a molecular formula of C14H17N3O5S and features a complex structure that includes a thiazole ring and a phenolic group. (-)-Anisomycin exhibits various biological activities, including anti-inflammatory and neuroprotective effects, making it a subject of interest in pharmacological research. It is also utilized in studies related to cellular signaling and stress responses. The compound is typically administered in laboratory settings for research purposes rather than as a therapeutic agent due to its potent effects on protein synthesis and potential cytotoxicity. Safety precautions are necessary when handling (-)-Anisomycin, as it can have significant biological effects on living organisms.

Formula: C₁₄H₁₉NO₄

InChI: InChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1

InChI key: InChIKey=YKJYKKNCCRKFSL-RDBSUJKOSA-N

SMILES: O=C(OC1C(O)CNC1CC2=CC=C(OC)C=C2)C

Synonyms:

• (2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate
• (2R,3S,4S)-2-(p-Methoxyphenylmethyl)-3-acetoxy-4-hydroxypyrrolidine
• (2R,3S,4S)-3-(acetyloxy)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidinium
• (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate
• (2S,3R,4R)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate
• 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate
• 2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate
• 2-p-Methoxyphenylmethyl-3-acetoxy-4-hydroxypyrrolidine
• 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R-(2-alpha,3-alpha,4-beta))-
• 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R-(2alpha,3alpha,4beta))-
• 3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, 3-acetate, (2R,3S,4S)-
• 3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, 3-acetate, (2S,3R,4R)-
• 3,4-Pyrrolidinediol, 2-(p-methoxybenzyl)-, 3-acetate, (2S,3R,4R)- (8CI)
• 3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)-
• 3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate, [2R-(2α,3α,4β)]-
• 4-Hydroxy-2-(4-Methoxybenzyl)Pyrrolidin-3-Yl Acetate
• Ai3-50846
• Antibiotic PA-106
• Brn 0020705
• Flagecidin
• Nsc 147340
• Nsc 76712
• Upjohn 204t3
• Wuningmeisu C
• 5-21-05-00523 (Beilstein Handbook Reference)
• Anisomycin
• (-)-Anisomycin

Anisomycin

CAS: 22862-76-6

• Formula: C₁₄H₁₉NO₄
• Purity: >96.0%(GC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 265.31

Anisomycin, 97%

CAS: 22862-76-6

A protein synthesis inhibitor. Causes apoptosis of PC12 Cells This Thermo Scientific Chemicals brand product …

• Formula: C₁₄H₁₉NO₄
• Purity: 97%
• Color and Shape: Powder, White
• Molecular weight: 265.31

3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate,(2R,3S,4S)-

CAS: 22862-76-6

• Formula: C₁₄H₁₉NO₄
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 265.305

Anisomycin

CAS: 22862-76-6

• Purity: 99.8%
• Molecular weight: 265.3g/mol

Anisomycin from Streptomyces griseolus

CAS: 22862-76-6

• Formula: C₁₄H₁₉NO₄
• Purity: By hplc: 98.46% (Typical Value in Batch COA)
• Color and Shape: white powder
• Molecular weight: 265.30g/mol

Anisomycin

CAS: 22862-76-6

• Formula: C₁₄H₁₉NO₄
• Purity: ≥ 98.0% (dried basis)
• Color and Shape: White crystalline powder
• Molecular weight: 265.31

Anisomycin

CAS: 22862-76-6

Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.

• Formula: C₁₄H₁₉NO₄
• Purity: 98.33% - 99.81%
• Color and Shape: White Crystalline Solid
• Molecular weight: 265.3

Anisomycin

CAS: 22862-76-6

Antibiotic of pyrrolidine class; protein synthesis inhibitor

• Formula: C₁₄H₁₉NO₄
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 265.31 g/mol

Anisomycin

CAS: 22862-76-6

Applications Anisomycin is an antibiotic agent, inhibiting protein synthesis and acting as a JNK activator. …

• Formula: C₁₄H₁₉NO₄
• Color and Shape: Neat
• Molecular weight: 265.3