CAS 22888-70-6

Silybin

Description:

Silybin, also known as silibinin, is a flavonoid compound derived from the milk thistle plant (Silybum marianum). It is primarily recognized for its hepatoprotective properties, making it a popular supplement for liver health. Silybin exhibits antioxidant activity, which helps to neutralize free radicals and reduce oxidative stress in cells. The compound is known to enhance the activity of certain liver enzymes and promote the regeneration of liver tissue. Additionally, silybin has been studied for its potential anti-inflammatory and anticancer effects, as it may inhibit the growth of various cancer cell lines. It is typically available in the form of silymarin, a complex of flavonolignans that includes silybin as its major active component. Silybin has low solubility in water, which can affect its bioavailability; however, various formulations, including phospholipid complexes, have been developed to improve its absorption in the body. Overall, silybin is valued for its therapeutic potential, particularly in the context of liver disorders and overall health.

Formula: C₂₅H₂₂O₁₀

InChI: InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23+,24-,25-/m1/s1

InChI key: InChIKey=SEBFKMXJBCUCAI-HKTJVKLFSA-N

SMILES: C(O)[C@@H]1[C@H](OC=2C(O1)=CC=C(C2)[C@H]3OC=4C(C(=O)[C@@H]3O)=C(O)C=C(O)C4)C5=CC(OC)=C(O)C=C5

Synonyms:

• (2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one
• (2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one
• (2R,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one
• 1,4-Benzodioxin, 4H-1-benzopyran-4-one deriv.
• 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin
• 4-Chromanone, 3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-
• 4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-
• 4H-1-Benzopyran-4-one, 2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, [2R-[2α,3β,6(2R*,3R*)]]-
• 7C3Mt
• Mepasil
• Milk Thistel P.E.
• Milk Thistle Extract
• Realsil
• Silibinin
• Silibinin A
• Silliver
• Silybin
• Silybin A
• Silybin b₁
• Silybine
• Silybum Extract
• Silybum marianum
• Silybum substance E₆
• Silymarin Group
• Silymarin I
• Silymarin MZ 80

Silybin (mixture of Silybin A and Silybin B)

CAS: 142797-34-0, 22888-70-6, 36804-17-8

Formula: C₂₅H₂₂O₁₀

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystaline

Molecular weight: 482.44

Ref: 3B-S0508

Silybin (Mixture of Silybin A and B)

CAS: 22888-70-6

Color and Shape: Mixture

Ref: 61-FOR0472.00

Silybin

CAS: 22888-70-6

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₂₅H₂₂O₁₀

Color and Shape: Off-White Powder

Molecular weight: 482.1213

Ref: 45-1612630

Silybin (Mixture of Silybin A and B)

CAS: 142797-34-0, 22888-70-6

Formula: C₂₅H₂₂O₁₀

Molecular weight: 482.44

Ref: 04-MM0472.00

(2R,3R)-3,5,7-trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-3,4-dihydro-2H-1-benzopyran-4-one

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Purity: 95%

Color and Shape: Solid

Molecular weight: 482.4362

Ref: IN-DA00I4I7

Silybin

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Purity: (HPLC) ≥ 98.0%

Color and Shape: White, off-white or yellow powder

Molecular weight: 482.44

Ref: 7W-GP4040

Silibinin

CAS: 22888-70-6

Silibinin

Purity: ≥95%

Molecular weight: 482.44g/mol

Ref: 54-BUP16622

Silybin (Mixture of Silybin A and B)

Controlled Product

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Color and Shape: Off White Solid

Molecular weight: 482.44

Ref: 86-MM0472.00

Silybin A

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Purity: 95%~99%

Molecular weight: 482.441

Ref: BP-BP5185

Silybin A

CAS: 22888-70-6

Silybin A

Formula: C₂₅H₂₂O₁₀

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 482.44g/mol

Ref: 54-BIC1034

Silybin A-d3

CAS: 22888-70-6

Formula: C₂₅H₁₉O₁₀D₃

Molecular weight: 485.47

Ref: 4Z-S-394

Silybin A

CAS: 22888-70-6

Formula: C₂₅H₂₂O₁₀

Color and Shape: Off-White Solid

Molecular weight: 482.45

Ref: 4Z-S-391

Silybin A

CAS: 22888-70-6

Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.

Formula: C₂₅H₂₂O₁₀

Purity: 97.98% - 98.37%

Color and Shape: Solid

Molecular weight: 482.44

Ref: TM-T1660

Silybin a

CAS: 22888-70-6

Oxygen-heterocyclic compound

Formula: C₂₅H₂₂O₁₀

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 482.44

Ref: 5G-82653

Silybin

CAS: 22888-70-6

Silybin is a bioactive compound, which is a flavonolignan, derived from the seeds of the Silybum marianum plant, commonly known as milk thistle. This compound is primarily obtained through solvent extraction and purification processes from the dried seeds of the plant.

Formula: C₂₅H₂₂O₁₀

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 482.44 g/mol

Ref: 3D-FS02332

(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one

CAS: 22888-70-6

Purity: 95%

Molecular weight: 482.4410095

Ref: 10-F870214

Silybin A

Controlled Product

CAS: 22888-70-6

Applications Silybin A is the 2R, 3R, 7‘R, 8‘R isomer of Silybin (S465850); a natural occurring flavolignan that exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells.
References Lee, D.Y.W, et al.: J. Nat. Prod., 66, 1171 (2003); Trappoliere, M., et al.: J. Hepatol., 50, 1102 (2009); Borsari, M., et al.: J. Inorg. Biochem., 85, 123 (2001)

Formula: C₂₅H₂₂O₁₀

Color and Shape: Neat

Molecular weight: 482.44

Ref: TR-S465855