CAS 2290-65-5

trimethylsilyl isothiocyanate

Description:

Trimethylsilyl isothiocyanate (TMS-ITC) is a chemical compound characterized by its isothiocyanate functional group, which is known for its reactivity and utility in organic synthesis. It features a trimethylsilyl group, which enhances its stability and solubility in organic solvents. TMS-ITC is typically a colorless to pale yellow liquid with a pungent odor, indicative of its isothiocyanate nature. It is used primarily as a reagent in the synthesis of thioureas and other nitrogen-containing compounds, as well as in the derivatization of amines and alcohols for analytical purposes. The presence of the trimethylsilyl group allows for improved volatility and ease of handling, making it a valuable tool in mass spectrometry and chromatography. Additionally, TMS-ITC can react with various nucleophiles, contributing to its versatility in synthetic organic chemistry. Safety precautions are necessary when handling this compound, as it can be irritating to the skin, eyes, and respiratory system.

Formula: C₄H₉NSSi

InChI: InChI=1/C4H9NSSi/c1-7(2,3)5-4-6/h1-3H3

InChI key: InChIKey=XLTUPERVRFLGLJ-UHFFFAOYSA-N

SMILES: N([Si](C)(C)C)=C=S

Synonyms:

• Isothiocyanatotrimethylsilane
• Silane, isothiocyanatotrimethyl-
• Trimethylisothiocyanatosilane
• Trimethylsilylisothiocyanate
• Trimethylsilyl isothiocyanate
• Trimethylsilyl isothiocyanate
• Trimethylsilylisothiocyanate,94%
• isothiocyanatotrimethyl-silan

Trimethylsilyl isothiocyanate, 94%

CAS: 2290-65-5

Trimethylsilyl isothiocyanate is used as derivatizing reagent during the synthesis of amino acid thiohydantoins. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product p

Formula: C₄H₉NSSi

Purity: 94%

Color and Shape: Clear to slightly turbid colorless to pale yellow, Liquid

Molecular weight: 131.27

Ref: 02-L03277

Trimethylsilyl isothiocyanate

CAS: 2290-65-5

Formula: C₄H₉NSSi

Purity: 99%

Color and Shape: Liquid

Molecular weight: 131.2715

Ref: IN-DA002LEE

Trimethylsilyl Isothiocyanate

CAS: 2290-65-5

Trimethylsilyl Isothiocyanate

Purity: 99%

Molecular weight: 131.27g/mol

Ref: 54-OR1030814

Trimethylsilylisothiocyanate

CAS: 2290-65-5

S19600 - Trimethylsilylisothiocyanate

Formula: C₄H₉NSSi

Purity: 95%

Color and Shape: Liquid, Clear

Molecular weight: 131.27

Ref: 10-S19600

Silane, isothiocyanatotrimethyl-

CAS: 2290-65-5

Trifluoroacetic acid is a reactive compound that can be used to produce amines by activation with trimethylsilyl. It is also used in the synthesis of other compounds, such as silanes and thiocyanates. Trifluoroacetic acid has been shown to be an effective treatment for autoimmune diseases, such as inflammatory bowel disease, alopecia areata, and rheumatoid arthritis. It has also been shown to inhibit the production of pro-inflammatory cytokines in human monocytes. Trifluoroacetic acid has chemical stability in organic solvents and does not react with water or alcohols.

Formula: C₄H₉NSSi

Purity: Min. 95%

Molecular weight: 131.27 g/mol

Ref: 3D-CAA29065