CAS 229016-73-3

Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, inner salt

Description:

Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, inner salt (CAS 229016-73-3) is a complex organic compound characterized by its unique structural features, including a pyridinium ring and multiple functional groups such as carboxylic acid, thiazole, and thiadiazole moieties. This compound exhibits properties typical of pyridinium salts, including solubility in polar solvents and potential biological activity. The presence of the phosphonoamino group suggests possible applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Its intricate structure may contribute to its reactivity and interaction with biological systems, making it a subject of interest for further research in drug design and synthesis. Overall, this compound exemplifies the diversity of organic chemistry and the potential for complex molecules to serve in therapeutic roles.

Formula: C₂₂H₂₁N₈O₈PS₄

InChI: InChI=1S/C22H21N8O8PS4/c1-3-38-26-13(16-25-21(43-28-16)27-39(35,36)37)17(31)24-14-18(32)30-15(20(33)34)12(9-40-19(14)30)42-22-23-11(8-41-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H4-,24,25,27,28,31,33,34,35,36,37)/b26-13-/t14-,19-/m1/s1

InChI key: InChIKey=ZCCUWMICIWSJIX-NQJJCJBVSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OCC)/C=3N=C(NP(=O)(O)O)SN3)=O)C2=O)(SCC1SC4=NC(=CS4)C=5C=C[N+](C)=CC5)[H]

Synonyms:

• Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, inner salt
• Pyridinium, 4-[2-[[(6R,7R)-2-carboxy-7-[[(2Z)-(ethoxyimino)[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]thio]-4-thiazolyl]-1-methyl-, inner salt

Ceftaroline fosamil inner salt

CAS: 229016-73-3

Ceftaroline fosamil (TAK-599) is a cephalosporin-derived MRSA antibiotic prodrug.

Formula: C₂₂H₂₁N₈O₈PS₄

Color and Shape: Solid

Molecular weight: 684.67

Ref: TM-T39816

Ceftaroline Fosamil Impurity 7

CAS: 229016-73-3

Formula: C₂₂H₂₁N₈O₈PS₄

Molecular weight: 684.69

Ref: 4Z-C-158008

Ceftaroline Fosamil Acetate d3

Controlled Product

CAS: 229016-73-3, 402741-13-3

Applications Ceftaroline Fosamil Inner salt-d3 is labelled Ceftaroline Fosamil inner salt (C243970) which is a cephalosporin antibiotic. It is active against methicillin-resistant Staphylococcus aureus (MRSA) and Gram-positive bacteria.
References Kanafani, Z., et al.: Future Microbiology, 4, 25 (2009); Parish, D,, et al.: Curr. Opinion Invest. Drugs, 9, 201 (2000)

Formula: C₂₂D₃H₁₈N₈O₈PS₄

Color and Shape: Neat

Molecular weight: 687.703

Ref: TR-C243972

Ceftarolin fosamil

CAS: 229016-73-3

Ceftaroline fosamil is an advanced antibiotic, which is a cephalosporin derived from synthetic sources with a broad spectrum of activity. It is a prodrug that, once metabolized, becomes active in the body, binding to penicillin-binding proteins (PBPs) of bacteria. This binding inhibits the proteins responsible for cell wall synthesis, leading to bacterial cell lysis and death.

Formula: C₂₂H₂₁N₈O₈PS₄

Purity: Min. 95%

Molecular weight: 684.69 g/mol

Ref: 3D-AC172986