CAS 22916-47-8: Miconazole

Description: Miconazole is an antifungal agent belonging to the imidazole class of compounds, primarily used to treat various fungal infections, including those caused by dermatophytes and yeasts. It exhibits broad-spectrum antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Miconazole is typically available in various formulations, including creams, powders, and oral gels, making it suitable for topical and systemic applications. The substance is characterized by its white to off-white crystalline powder form, with a relatively low solubility in water but better solubility in organic solvents. Miconazole is known for its minimal systemic absorption when applied topically, which reduces the risk of systemic side effects. Additionally, it may exhibit some antibacterial properties, making it useful in treating mixed infections. As with any medication, potential side effects can occur, including local irritation or allergic reactions, and it is important to use it under the guidance of a healthcare professional.

Formula: C₁₈H₁₄Cl₄N₂O

InChI: InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2

InChI key: InChIKey=BYBLEWFAAKGYCD-UHFFFAOYSA-N

SMILES: ClC1=CC=C(C(Cl)=C1)COC(C2=CC=C(Cl)C=C2Cl)CN3C=NC=C3

Synonyms:

• 1-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
• 1-(2-(2,4-Dichlorophenyl)-2-((2,4-Dichlorophenyl)Methoxy)Ethyl)-1H-Imidazole
• 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
• 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
• 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-
• 2-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
• Daktanol
• Daktarin IV
• Florid-F
• Imidazole, 1-[2,4-dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl]-
• Lauriad
• Loramyc
• Miconazol
• Mjr 1762
• Monistat IV
• Nsc 170986
• R 18134
• Zimybase
• Miconazole

Miconazole, 97%

CAS: 22916-47-8

Miconazole, is used as an antifungal inhibitor of aromatase. Miconazole has been shown to promote …

• Formula: C₁₈H₁₄Cl₄N₂O
• Purity: 97%
• Color and Shape: White, Powder
• Molecular weight: 416.12

Miconazole CRS

CAS: 22916-47-8

Miconazole

CAS: 22916-47-8

Compounds containing an unfused imidazole ring (whether

• Formula: C₁₈H₁₄Cl₄N₂O
• Color and Shape: Powder
• Molecular weight: 413.98602

Miconazole

CAS: 22916-47-8

Miconazole (R18134) is an imidazole antifungal agent that is used topically and by intravenous infusion.

• Formula: C₁₈H₁₄Cl₄N₂O
• Purity: 100% - 99.78%
• Color and Shape: Solid
• Molecular weight: 416.13

1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-

CAS: 22916-47-8

• Formula: C₁₈H₁₄Cl₄N₂O
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 416.1286

Miconazole, EP grade

CAS: 22916-47-8

• Formula: C₁₈H₁₄Cl₄N₂O
• Purity: 99.0 - 101.0 % (dried substance)
• Color and Shape: White or almost white powder
• Molecular weight: 416.13

Miconazole

CAS: 22916-47-8

• Formula: C₁₈H₁₄Cl₄N₂O
• Purity: 99.0 - 101.0 % (anhydrous basis)
• Color and Shape: White or almost white powder
• Molecular weight: 416.13

Miconazole

CAS: 22916-47-8

• Purity: ≥98%
• Molecular weight: 416.13g/mol

Miconazole

CAS: 22916-47-8

• Purity: 99%
• Molecular weight: 416.13g/mol

Miconazole, USP grade

CAS: 22916-47-8

• Formula: C₁₈H₁₄Cl₄N₂O
• Molecular weight: 416.13

Miconazole

CAS: 22916-47-8

• Formula: C₁₈H₁₄Cl₄N₂O
• Color and Shape: Neat
• Molecular weight: 416.13

Miconazole

CAS: 22916-47-8

• Formula: C₁₈H₁₄Cl₄N₂O
• Color and Shape: Neat
• Molecular weight: 416.13

Miconazole

CAS: 22916-47-8

Applications Antifungal (topical). References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, …

• Formula: C₁₈H₁₄Cl₄N₂O
• Color and Shape: White
• Molecular weight: 416.13

Miconazole

CAS: 22916-47-8

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 416.1199951171875

Miconazole

CAS: 22916-47-8

Anti-fungal; sterol 14α-demethylase inhibitor

• Formula: C₁₈H₁₄Cl₄N₂O
• Purity: Min. 95 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 416.13 g/mol