CAS 229305-39-9

D-γ-Glutamyl-L-tryptophan

Description:

D-γ-Glutamyl-L-tryptophan is a dipeptide composed of the amino acids D-γ-glutamic acid and L-tryptophan. It is characterized by its unique structure, which includes a γ-carboxyl group from the glutamic acid and an indole side chain from tryptophan, contributing to its biochemical properties. This compound is known for its potential roles in various biological processes, including neurotransmission and metabolic pathways. D-γ-Glutamyl-L-tryptophan may exhibit specific interactions with receptors or enzymes due to the presence of the tryptophan moiety, which is a precursor for serotonin, a key neurotransmitter. The compound is typically soluble in water, reflecting the polar nature of its constituent amino acids. Its stability and reactivity can be influenced by factors such as pH and temperature. Research into this dipeptide may provide insights into its therapeutic potential, particularly in neuropharmacology and nutrition. As with many peptides, its synthesis can be achieved through solid-phase peptide synthesis or other chemical methods, allowing for the study of its biological functions and applications.

Formula: C₁₆H₁₉N₃O₅

InChI: InChI=1S/C16H19N3O5/c17-11(15(21)22)5-6-14(20)19-13(16(23)24)7-9-8-18-12-4-2-1-3-10(9)12/h1-4,8,11,13,18H,5-7,17H2,(H,19,20)(H,21,22)(H,23,24)/t11-,13+/m1/s1

InChI key: InChIKey=CATMPQFFVNKDEY-YPMHNXCESA-N

SMILES: C([C@H](NC(CC[C@H](C(O)=O)N)=O)C(O)=O)C=1C=2C(NC1)=CC=CC2

Synonyms:

• <span class="text-smallcaps">D</smallcap>-γ-Glutamyl-<smallcap>L</span>-tryptophan
• <span class="text-smallcaps">L</smallcap>-Tryptophan, <smallcap>D</span>-γ-glutamyl-
• Golotimod
• H-D-Glu(Trp-Oh)-Oh
• Scv 07
• γ-D-glutamyl-L-tryptophan
• L-Tryptophan, D-γ-glutamyl-
• D-γ-Glutamyl-L-tryptophan

H-D-Glu(Trp-OH)-OH

CAS: 229305-39-9

An immunomodulating dipeptide. γ-D-Glu-Trp reduced adenylate cyclase activity in macrophage and thymocyte membranes.

Formula: C₁₆H₁₉N₃O₅

Purity: > 98%

Color and Shape: Whitish Powder

Molecular weight: 333.34

Ref: 01-4033407

(R)-2-Amino-5-(((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoic acid

CAS: 229305-39-9

Formula: C₁₆H₁₉N₃O₅

Purity: 98%

Molecular weight: 333.3392

Ref: IN-DA00BD95

Golotimod

CAS: 229305-39-9

Golotimod

Purity: ≥98%

Molecular weight: 333.34g/mol

Ref: 54-BUP02139

Golotimod

CAS: 229305-39-9

Golotimod (SCV 07) is an antimicrobial active dipeptide with immunomodulatory activity for the study of recurrent genital herpes simplex virus 2 infections.

Formula: C₁₆H₁₉N₃O₅

Purity: 99.88% - 99.98%

Color and Shape: Solid

Molecular weight: 333.34

Ref: TM-T11449L

H-D-Glu(Trp-OH)-OH

CAS: 229305-39-9

H-D-Glu(Trp-OH)-OH is a synthetic peptide that has been shown to inhibit the replication of the herpes simplex virus (HSV). It binds to toll-like receptor 3 and 4 on cells, which may inhibit HSV replication. This compound has also been shown to be a potent inhibitor of HIV, as well as hepatitis B and C. H-D-Glu(Trp-OH)-OH has been shown to cause lung damage in mice. The mechanism for this effect is unknown, but it may involve an increase in reactive oxygen species or other cell signaling pathways.

Formula: C₁₆H₁₉N₃O₅

Purity: Min. 95%

Molecular weight: 333.34 g/mol

Ref: 3D-FG108327