CAS 2295-31-0
:Thiazolidinedione
Description:
Thiazolidinedione, specifically referring to the compound with CAS number 2295-31-0, is a member of a class of drugs known as thiazolidinediones (TZDs), which are primarily used in the management of type 2 diabetes. This compound features a thiazolidine ring, which is a five-membered heterocyclic structure containing both sulfur and nitrogen atoms. Thiazolidinediones function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ), which plays a crucial role in glucose and lipid metabolism. The pharmacological effects of thiazolidinediones include improved insulin sensitivity, reduced blood glucose levels, and modulation of fatty acid storage and glucose metabolism. However, their use can be associated with side effects such as weight gain, fluid retention, and potential cardiovascular risks. The compound is typically administered orally and is often used in combination with other antidiabetic medications. As with any medication, it is important for patients to discuss potential benefits and risks with their healthcare provider.
Formula:C3H3NO2S
InChI:InChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
InChI key:InChIKey=ZOBPZXTWZATXDG-UHFFFAOYSA-N
SMILES:O=C1NC(=O)SC1
Synonyms:- 1,3-Thiazolidine-2,4-Dione
- 2,4(3H,5H)-Thiazoledione
- 2,4-Dioxo-1,3-thiazolidine
- 2,4-Dioxothiazolidine
- 2,4-Thiadolidinedione
- 2-Hydroxy-4,5-dihydro-1,3-thiazol-4-one
- 2-Thiazolin-4-one, 2-hydroxy-
- Nsc 6745
- Otava-Bb Bb7112440002
- TZD
- Thiazole-2,4-dione
- Thiazolidin-2,4-dion
- Thiazolidin-2,4-dione
- Thiazolidine-2,4-dione
- Thiazolidinedione
- Thiazolidinedione-2,4
- Tiazolidina-2,4-Diona
- Timtec-Bb Sbb000047
- U 25560
- See more synonyms
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Found 9 products.
2,4-Thiazolidinedione
CAS:Formula:C3H3NO2SPurity:>98.0%(GC)(T)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:117.122,4-Thiazolidinedione, 99%
CAS:<p>2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity. This Thermo Scientific Chemicals brand product was or</p>Formula:C3H3NO2SPurity:99%Color and Shape:Crystalline powder or crystals, White to cream or pale yellowMolecular weight:117.122,4-Thiazolidinedione
CAS:Formula:C3H3NO2SPurity:≥ 99.0%Color and Shape:White to off-white powderMolecular weight:117.131,3-Thiazolidine-2,4-dione
CAS:1,3-Thiazolidine-2,4-dioneFormula:C3H3NO2SPurity:99%Color and Shape: white solidMolecular weight:117.13g/mol2,4-Thiazolidinedione
CAS:Controlled Product<p>Applications Inhibitor of enzyme.<br>References Martinez, A., et al.: J. Med. chem., 23, 7103 (2005)<br></p>Formula:C3H3NO2SColor and Shape:White To Light YellowMolecular weight:117.13Thiazolidine-2,4-dione
CAS:<p>Thiazolidine-2,4-dione (THZ) is a drug that has been shown to be an orally active, anti-inflammatory agent with postprandial blood glucose lowering properties. It inhibits the nuclear factor kappa B (NF-κB) binding activity and suppresses inflammation in vitro and in vivo. THZ also has hypoglycemic effects and may be used as an oral hypoglycemic agent for the treatment of diabetes mellitus type 2. THZ is not active against bowel disease or atherosclerosis. It interacts with other drugs, such as statins, which reduce its hypoglycemic effects. This drug also intercalates into DNA and binds to response elements related to inflammation and insulin signalling pathways.</p>Formula:C3H3NO2SPurity:Min. 89.0%Color and Shape:PowderMolecular weight:117.13 g/mol
