CAS 2296729-00-3: Pyrido[2,3-d]pyrimidin-2(1H)-one,6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-,(1R)-

Description: Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-, (1R)- is a complex organic compound characterized by its multi-ring structure, which includes a pyrido-pyrimidine core. This compound features several functional groups, including fluorine atoms, a hydroxyl group, and a piperazine moiety, contributing to its potential biological activity. The presence of fluorine atoms often enhances lipophilicity and metabolic stability, while the hydroxyl group can participate in hydrogen bonding, influencing solubility and reactivity. The compound's stereochemistry, indicated by the (1R) configuration, suggests specific spatial arrangements that may affect its interaction with biological targets. Such compounds are typically investigated for their pharmacological properties, including potential applications in medicinal chemistry, particularly in the development of therapeutics targeting various diseases. Overall, the structural complexity and functional diversity of this compound make it a subject of interest in chemical and pharmaceutical research.

Synonyms:

• Sotorasib
• Storasib
• 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
• AMG510

(1R)-4-((S)-4-Acryloyl-2-Methylpiperazin-1-Yl)-6-Fluoro-7-(2-Fluoro-6-Hydroxyphenyl)-1-(2-Isopropyl-4-Methylpyridin-3-Yl)Pyrido[2,3-D]Pyrimidin-2(1H)-One

CAS: 2296729-00-3

• Purity: 98%
• Molecular weight: 560.59g/mol

Sotorasib

CAS: 2296729-00-3

• Purity: 99%
• Molecular weight: 560.59g/mol

Sotorasib

CAS: 2296729-00-3

Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.

• Formula: C₃₀H₃₀F₂N₆O₃
• Purity: 98% - 99.89%
• Color and Shape: Solid
• Molecular weight: 560.59

AMG 510

CAS: 2296729-00-3

KRAS G12C inhibitor

• Formula: C₃₀H₃₀F₂N₆O₃
• Purity: (%) Min. 98%
• Color and Shape: Powder
• Molecular weight: 560.59 g/mol