CAS 2299-46-9

Prednisolone EP Impurity G (20(S)-Hydroxy Prednisolone)

CAS: 2299-46-9

Formula: C₂₁H₃₀O₅

Color and Shape: Gray Solid

Molecular weight: 362.47

Ref: 4Z-P-11106

(20S)-Hydroxyprednisolone

Controlled Product

CAS: 2299-46-9

Color and Shape: Neat

Ref: 86-MM0193.02

20(S)-Hydroxy Prednisolone-d4

CAS: 2299-46-9

Formula: C₂₁H₂₆D₄O₅

Molecular weight: 366.49

Ref: 4Z-P-111124

20(S)-Hydroxy Prednisolone

Controlled Product

CAS: 2299-46-9

Impurity Prednisolone EP Impurity G
Applications 20(S)-Hydroxy Prednisolone (Prednisolone EP Impurity G) is a Prednisolone (P703740) metabolite.
References Kim, H., et al.: J. Med. Chem., 30, 2239 (1987), Addison, R., et al.: J. Steroid Biochem., Mol. Biol., 39, 83 (1991),

Formula: C₂₁H₃₀O₅

Color and Shape: Neat

Molecular weight: 362.46

Ref: TR-H952360

20α-Hydroxy prednisolone

Controlled Product

CAS: 2299-46-9

20a-Hydroxy prednisolone is an impurity that is found in the ophthalmic drug prednisolone. It has been shown to affect the perfusion of tissues in a rat's eye and can be used to validate analytical methods for quantifying prednisolone. The chromatographic method developed by Agilent was validated using tissue culture and reversed-phase chromatography, with excellent recoveries and reproducibility. The validation process also detected other impurities that were present at low levels (1%) such as 20-hydroxy-prednisolone, 17alpha-hydroxy-prednisolone, 18a-hydroxy-prednisolone, 19a-hydroxy-prednisolone, 21a-hydroxy-prednisolone, and 22a-hydroxy-prednisolone.

Formula: C₂₁H₃₀O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 362.46 g/mol

Ref: 3D-FH24097

Prednisolone EP Impurity G

CAS: 2299-46-9

Formula: C₂₁H₃₀O₅

Molecular weight: 362.47

Ref: ST-EA-CP-P20007