CAS 22994-85-0: Benznidazole

Description: Benznidazole is a nitroimidazole derivative primarily used as an antiparasitic agent, particularly in the treatment of Chagas disease caused by the Trypanosoma cruzi parasite. It exhibits a molecular formula of C12H10N4O5S and has a molecular weight of approximately 298.3 g/mol. The compound is characterized by its nitro group, which is essential for its biological activity, and a thiazole ring that contributes to its pharmacological properties. Benznidazole is typically administered orally and is known for its ability to inhibit the growth of the parasite by interfering with its metabolic processes. The drug is generally well-tolerated, although it may cause side effects such as allergic reactions, gastrointestinal disturbances, and neurological symptoms in some patients. Its mechanism of action involves the generation of reactive oxygen species, leading to oxidative stress in the parasite. Benznidazole is an important therapeutic option in regions where Chagas disease is endemic, and ongoing research continues to explore its efficacy and safety profile in various populations.

Formula: C₁₂H₁₂N₄O₃

InChI: InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)

InChI key: InChIKey=CULUWZNBISUWAS-UHFFFAOYSA-N

SMILES: O=C(NCC=1C=CC=CC1)CN2C=CN=C2N(=O)=O

Synonyms:

• 1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-
• 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide
• Benznidazol
• Benzonidazol
• Benzonidazole
• Imidazole-1-acetamide, N-benzyl-2-nitro-
• N-Benzyl-2-nitroimidazol-1-yl-acetamide
• N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide
• N-benzyl-2-nitro-1H-imidazole-1-acetamide
• NSC 299972
• Radanil
• Ro 07-1051
• Ro 71051
• Rochagan
• Benznidazole

1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-

CAS: 22994-85-0

• Formula: C₁₂H₁₂N₄O₃
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 260.2487

Benznidazole

CAS: 22994-85-0

• Formula: C₁₂H₁₂N₄O₃
• Color and Shape: Off-White Solid
• Molecular weight: 260.25

N-Benzyl-2-Nitro-1H-Imidazole-1-Acetamide

CAS: 22994-85-0

• Purity: 97%
• Molecular weight: 260.25g/mol

Benznidazole

CAS: 22994-85-0

• Formula: C₁₂H₁₂N₄O₃
• Molecular weight: 260.25

Benznidazol

CAS: 22994-85-0

Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production …

• Formula: C₁₂H₁₂N₄O₃
• Purity: 100% - 99.53%
• Color and Shape: Solid
• Molecular weight: 260.25

Benznidazole

CAS: 22994-85-0

Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The …

• Formula: C₁₂H₁₂N₄O₃
• Color and Shape: Neat
• Molecular weight: 260.25

Benznidazole-d7

CAS: 22994-85-0

Applications Benznidazole-D7 is a labelled analogue of Benznidazole (B197925).

• Formula: C₁₂H₅D₇N₄O₃
• Color and Shape: Neat
• Molecular weight: 267.29

Benznidazole

CAS: 22994-85-0

Please enquire for more information about Benznidazole including the price, delivery time and more detailed …

• Formula: C₁₂H₁₂N₄O₃
• Purity: Min. 97 Area-%
• Color and Shape: White Powder
• Molecular weight: 260.25 g/mol