CAS 229975-97-7: Atazanavir Sulfate
Description:Atazanavir sulfate is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of drugs known as protease inhibitors, which work by inhibiting the protease enzyme, crucial for the viral replication process. The chemical formula for atazanavir sulfate reflects its complex structure, which includes a sulfonate group, enhancing its solubility and bioavailability. This compound is typically administered orally and is known for its once-daily dosing regimen, which improves patient adherence to treatment. Atazanavir is characterized by its relatively favorable side effect profile compared to other protease inhibitors, although it can still cause issues such as hyperbilirubinemia and gastrointestinal disturbances. It is often used in combination with other antiretroviral agents to achieve a more effective viral suppression. The CAS number 229975-97-7 uniquely identifies this compound, facilitating its recognition in chemical databases and regulatory documents. Overall, atazanavir sulfate plays a significant role in modern HIV therapy, contributing to improved health outcomes for individuals living with the virus.
Formula:C38H52N6O7·H2O4S
InChI:InChI=1S/C38H52N6O7.H2O4S/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28;1-5(2,3)4/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47);(H2,1,2,3,4)/t29-,30-,31+,32+;/m0./s1
InChI key:InChIKey=DQSGVVGOPRWTKI-QVFAWCHISA-N
SMILES:O=C(OC)NC(C(=O)NN(CC=1C=CC(=CC1)C2=NC=CC=C2)CC(O)C(NC(=O)C(NC(=O)OC)C(C)(C)C)CC=3C=CC=CC3)C(C)(C)C.O=S(=O)(O)O
- Synonyms:
- 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3S,8S,9S,12S)-, sulfate (1:1)
- 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, dimethyl ester, (3S,8S,9S,12S)-, sulfate (1:1) (salt)
- Atazanavir Sulphate
- Atazor
- Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate
- Reyataz
- methyl {(5S,10S,11S,14S)-11-benzyl-5-tert-butyl-10-hydroxy-15,15-dimethyl-3,6,13-trioxo-8-[4-(pyridin-2-yl)benzyl]-2-oxa-4,7,8,12-tetraazahexadecan-14-yl}carbamate sulfate (1:1) (non-preferred name)
- Atazanavir sulfate
