CAS 23031-25-6

Terbutaline

Description:

Terbutaline is a synthetic medication primarily used as a bronchodilator in the treatment of asthma and other respiratory conditions. It belongs to the class of drugs known as beta-2 adrenergic agonists, which work by relaxing the muscles of the airways, thereby facilitating easier breathing. Terbutaline is characterized by its ability to selectively stimulate beta-2 adrenergic receptors, leading to bronchodilation with minimal cardiovascular effects. The substance is typically administered via inhalation, oral tablets, or subcutaneous injection, depending on the clinical scenario. Terbutaline has a relatively short half-life, which allows for quick onset of action, making it effective for acute asthma attacks. Additionally, it may exhibit some anti-inflammatory properties, although its primary function is as a bronchodilator. Common side effects can include tremors, nervousness, and increased heart rate, which are generally mild. As with any medication, it is essential to use terbutaline under medical supervision to manage potential interactions and contraindications effectively.

Formula: C₁₂H₁₉NO₃

InChI: InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3

InChI key: InChIKey=XWTYSIMOBUGWOL-UHFFFAOYSA-N

SMILES: C(CNC(C)(C)C)(O)C1=CC(O)=CC(O)=C1

Synonyms:

• (2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
• 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-
• 1-(3, 5-Dihydroxyphenyl)-2-(t-butylamino) ethanol
• 1-(3,5-Dihydroxyphenyl)-2-(tert-butylamino)ethanol
• 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol
• 5-[2-(Tert-Butylamino)-1-Hydroxyethyl]Benzene-1,3-Diol Sulfate (1:1)
• 5-[2-(tert-Butylamino)-1-hydroxyethyl]benzene-1,3-diol
• 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol
• 5-{1-Hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}-1,3-benzenediol
• 5-{1-Hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}-1,3-benzoldiol
• Aerodur
• Ar-D 080301
• Ar-Do80301
• Benzyl alcohol, α-[(tert-butylamino)methyl]-3,5-dihydroxy-
• Brican
• Bricanyl
• Bricar
• Bricaril
• Bricyn
• Fasma
• Kwd 2019
• Terbutalin
• Terbutalino
• Terbutaline
• 5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol USP/EP/BP
• (R)-α-[(tert-Butylamino)methyl]-3,5-dihydroxybenzyl alcohol
• CarButerol impurity A
• Terbutaline & Terbutaline Sulfate
• 5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol
• (S)-α-[(tert-Butylamino)methyl]-3,5-dihydroxybenzyl alcohol
• Bambuterol impurity 1
• Terbutaline-d3
• Terbutaline Impurity 36
• Bambuterol EP Impurity A
• C07129
• 5-[(S)-1-Hydroxy-2-(tert-butylamino)ethyl]benzene-1,3-diol
• Terbutaline Impurity 29
• rac-5-[(R*)-2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol

Terbutaline

CAS: 23031-25-6

Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol

Formula: C₁₂H₁₉NO₃

Purity: 99.12%

Color and Shape: Solid

Molecular weight: 225.3

Ref: TM-T8810

Terbutaline-d3 (1-hydroxyethyl-1,2,2-d3)

CAS: 23031-25-6

Purity: 92 atom % D

Color and Shape: Off-White Solid

Molecular weight: 228.31

Ref: 3U-D7115

Terbutaline 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 23031-25-6

Formula: C₁₂H₁₉NO₃

Color and Shape: Single Solution

Molecular weight: 225.28

Ref: 04-A17294950AL-1000

GB/T 22286-2008 11 β-Agonists 100 µg/mL in Methanol

Controlled Product

CAS: 21898-19-1, 21912-49-2, 23031-25-6, 51022-70-9, 54238-51-6, 54239-37-1, 54239-39-3, 56341-08-3, 579-56-6, 78982-84-0, 90274-24-1

Color and Shape: Mixture

Ref: 04-A50000096ME

Terbutaline-d3 (1-hydroxyethyl-1,2,2-d3)

Controlled Product

CAS: 23031-25-6

Formula: C₁₂H₁₆D₃NO₃

Color and Shape: Light Brown

Molecular weight: 228.15532

Ref: TR-T109751

Terbutaline

Controlled Product

CAS: 23031-25-6

Applications Terbutaline is a beta-adrenoceptor agonist used to treat asthma and premature labor.
References O'Byrne, P. M., et al.: Trials, 18, 12 (2017); Vijftigschild, L. A. W., et al.: Eur. Respir. J., 48, 768 (2016); Fang, M., et al.: Xiandai Zhenduan Yu Zhiliao, 25, 4877 (2014)

Formula: C₁₂H₁₉NO₃

Color and Shape: White To Light Brown

Molecular weight: 225.28

Ref: TR-T109763

Terbutaline-D9 (Tert-butyl-D9) Acetate

Controlled Product

CAS: 23031-25-6

Formula: C₁₂D₉H₁₀NO₃·C₂H₄O₂

Color and Shape: Neat

Molecular weight: 294.39

Ref: TR-T946324

Bambuterol EP Impurity A

CAS: 23031-25-6

Formula: C₁₂H₁₉NO₃

Molecular weight: 225.3

Ref: ST-EA-CP-B109002

5-[2-[(1,1-Dimethylethyl)-amino]-1-hydroxyethyl]-1,3-benzenediol

Controlled Product

CAS: 23031-25-6

5-[2-[(1,1-Dimethylethyl)-amino]-1-hydroxyethyl]-1,3-benzenediol is a drug that is used to treat asthma and other allergic reactions. It is a bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. Terbutaline has been shown to be effective against non-steroidal anti-inflammatory agents, which are drugs that reduce inflammation. Terbutaline has also been shown to increase systolic pressure in people with high blood pressure and can cause heart disease in those with structural heart disease. The drug is not active against bowel disease.

Formula: C₁₂H₁₉NO₃

Purity: Min. 95%

Molecular weight: 225.28 g/mol

Ref: 3D-FD157433

1,3-Benzenediol, 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-

CAS: 23031-25-6

Formula: C₁₂H₁₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 225.2842

Ref: IN-DA002LYQ