CAS 2304-89-4

3-Oxocholic acid

Description:

3-Oxocholic acid, also known as 3-oxo-5β-cholanoic acid, is a bile acid derivative characterized by its steroid structure, which includes a hydroxyl group and a ketone functional group. It is a naturally occurring compound in the human body, playing a role in the metabolism of lipids and the emulsification of fats. The presence of the ketone group at the C3 position distinguishes it from other bile acids, contributing to its unique biochemical properties. This compound is typically found in bile and is involved in the digestion and absorption of dietary fats. Its solubility is influenced by the presence of hydroxyl groups, which enhance its interaction with water. 3-Oxocholic acid can also participate in various biochemical pathways, including those related to cholesterol metabolism. As a research subject, it has garnered interest for its potential implications in understanding metabolic disorders and liver function. Overall, 3-oxocholic acid is an important molecule in both physiological and pathological contexts within the field of biochemistry.

Formula: C₂₄H₃₈O₅

InChI: InChI=1S/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-14,16-20,22,26-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=OEKUSRBIIZNLHZ-DJDNIQJZSA-N

SMILES: O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(CC(=O)CC4)[H])[H])[H])[H]

Synonyms:

• Cholan-24-oic acid, 7,12-dihydroxy-3-oxo-, (5β,7α,12α)-
• (5β,7α,12α)-7,12-Dihydroxy-3-oxocholan-24-oic acid
• 5β-Cholanic acid, 7α,12α-dihydroxy-3-oxo-
• 7α,12α-Dihydroxy-3-keto-5β-cholanic acid
• 5β-Cholan-24-oic acid, 7α,12α-dihydroxy-3-oxo-

(5β,7α,12α)-7,12-Dihydroxy-3-oxocholan-24-oic acid

CAS: 2304-89-4

Formula: C₂₄H₃₈O₅

Purity: %

Color and Shape: Solid

Molecular weight: 406.5555

Ref: IN-DA00C2J9

3-​Oxocholic acid

CAS: 2304-89-4

3-​Oxocholic acid

Purity: ≥98%

Molecular weight: 406.56g/mol

Ref: 54-BUP10686

3-Oxo Deoxycholic Acid

CAS: 2304-89-4

Formula: C₂₄H₃₈O₅

Color and Shape: White To Off-White Solid

Molecular weight: 406.56

Ref: 4Z-C-5712

3-​Oxocholic acid

CAS: 2304-89-4

3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-

Formula: C₂₄H₃₈O₅

Purity: 99.44%

Color and Shape: Solid

Molecular weight: 406.56

Ref: TM-T19124

7a,12a-Dihydroxy-3-oxo-5b-cholan-24-oic Acid

CAS: 2304-89-4

Formula: C24H38O5

Purity: >96%

Color and Shape: Solid

Molecular weight: 406.56

Ref: 48-65-1106

3-Oxocholic Acid

CAS: 2304-89-4

Formula: C24H38O5

Purity: >95%

Color and Shape: Solid

Molecular weight: 406.56

Ref: 48-65-1103

3-Oxo-7α,12α-hydroxy-5β-cholanoic Acid

Controlled Product

CAS: 2304-89-4

Stability Hygroscopic
Applications 3-Oxo-7α,12α-hydroxy-5β-cholanoic Acid is a keto bile acid derivative.
References Bortolini, O. et al.: Tetra., 62, 4482 (2006); Bortolini, O. et al.: J. Org. Chem., 67, 5802 (2002); Iguchi, Y. et al.: Biol. Pharm. Bull., 34, 1 (2011);

Formula: C₂₃H₃₆O₆

Color and Shape: Off-White To Light Beige

Molecular weight: 408.53

Ref: TR-O856895

3-Oxo-7±,12±-hydroxy-5²-cholanoic Acid

Controlled Product

CAS: 2304-89-4

3-Oxo-7±,12±-hydroxy-5²-cholanoic Acid is a bile acid that is important for the absorption of dietary lipids. It is produced by the liver and secreted into the bile, where it is used to solubilize lipids in the small intestine. In humans, 3-Oxo-7±,12±-hydroxy-5²-cholanoic Acid has been shown to inhibit cancer growth and promote regression of tumors. It has also been shown to increase the production of matricellular proteins in intestinal cells and may have a role in regulation of hepatic cytochrome P450 enzymes.

Formula: C₂₄H₃₈O₅

Purity: Min. 95%

Molecular weight: 406.56 g/mol

Ref: 3D-CAA30489