CAS 2304-94-1

N-benzyloxycarbonyl-β-alanine

Description:

N-Benzyloxycarbonyl-β-alanine, also known as Z-β-alanine, is an amino acid derivative characterized by the presence of a benzyloxycarbonyl (Z) protecting group on the amino group of β-alanine. This compound is typically a white to off-white crystalline solid, soluble in organic solvents such as methanol and dimethyl sulfoxide, but less soluble in water. It has a molecular structure that includes a carboxylic acid group, an amino group, and a side chain that features a benzyl group, which contributes to its hydrophobic characteristics. The Z group serves as a protective moiety, making it useful in peptide synthesis, particularly in the formation of peptide bonds where selective protection of the amino group is required. N-Benzyloxycarbonyl-β-alanine is often utilized in biochemical research and pharmaceutical applications, including the synthesis of various bioactive compounds and peptides. Its stability and reactivity under specific conditions make it a valuable intermediate in organic synthesis.

Formula: C₁₁H₁₃NO₄

InChI: InChI=1/C11H13NO4/c13-10(14)6-7-12-11(15)16-8-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,15)(H,13,14)

InChI key: InChIKey=GEVGRLPYQJTKKS-UHFFFAOYSA-N

SMILES: C(OC(NCCC(O)=O)=O)C1=CC=CC=C1

Synonyms:

• 3-(Benzyloxycarbonylamino)propanoic acid
• 3-(Benzyloxycarbonylamino)propionic acid
• 3-(Cbz-amino)-propanoic acid
• 3-[N-(Benzyloxycarbonyl)amino]propionic acid
• Carbobenzoxy-β-alanine
• Carbobenzyloxy-beta-alanine
• Cbz-Beta-Alanine
• N-CBZ-β-alanine
• N-Carbobenzoxy-β-alanine
• N-Carbobenzoyl-β-alanine
• N-Carbobenzyloxy-β-alanine
• N-[(Benzyloxy)carbonyl]-beta-alanine
• N-[(Phenylmethoxy)carbonyl]-β-alanine
• NSC 17161
• NSC 28943
• NSC 657842
• Z-β-Ala-OH
• beta-Alanine, N-[(phenylmethoxy)carbonyl]-
• β-Alanine, N-[(phenylmethoxy)carbonyl]-
• β-Alanine, N-carboxy-, N-benzyl ester
• N-(Benzyloxycarbonyl)-β-alanine
• Cbz--alanine
• N-BETA-CBZ-BETA-ALANINE
• RARECHEM AL CF 0961
• Z-GLY(C*CH2)-OH
• N-BETA-CARBOBENZOXY-BETA-ALANINE
• BENZYLOXYCARBONYL-BETA-ALANINE
• N-CARBOBENZOXY-BETA-ALANINE
• Z-SS-ALA-OH
• CBZ-SS-ALA-OH
• N-BENZYLOXYCARBONYL-BETA-ALANINE
• CBZ-BETA-ALA-OH
• N-CBZ-BETA-ALANINE
• Z-NH-(CH2)2-COOH
• Z-BETA-ALA-OH
• N-CBZ-B-ALANINE CRYSTALLINE
• Z-SS ALA

N-Carbobenzoxy-β-alanine

CAS: 2304-94-1

Formula: C₁₁H₁₃NO₄

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 223.23

Ref: 3B-C0640

N-Benzyloxycarbonyl-β-alanine, 98%

CAS: 2304-94-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₁₃NO₄

Purity: 98%

Molecular weight: 223.23

Ref: 02-H59293

Z-β-Ala-OH

CAS: 2304-94-1

Bachem ID: 4000236.

Formula: C₁₁H₁₃NO₄

Purity: > 99%

Color and Shape: White

Molecular weight: 223.23

Ref: 01-4000236

β-Alanine, N-[(phenylmethoxy)carbonyl]-

CAS: 2304-94-1

Formula: C₁₁H₁₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 223.2252

Ref: IN-DA002LZ5

N-Cbz-β-alanine

CAS: 2304-94-1

N-Cbz-β-alanine

Purity: 98%

Molecular weight: 223.23g/mol

Ref: 54-OR350305

Z-β-Ala-OH

CAS: 2304-94-1

Formula: C₁₁H₁₃NO₄

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 223.23

Ref: 7W-GM1130

Z-B-Ala-OH

CAS: 2304-94-1

M03073 - Z-B-Ala-OH

Formula: C₁₁H₁₃NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 223.228

Ref: 10-M03073

Z-b-Alanine extrapure, 99%

CAS: 2304-94-1

Formula: C₁₁H₁₃NO₄

Purity: min. 99 %

Color and Shape: White, Crystalline powder

Molecular weight: 223.21

Ref: SR-68280

N-Carbobenzoxy-β-alanine

Controlled Product

CAS: 2304-94-1

Applications N-Carbobenzoxy-β-alanine has been utilized for various synthesis applications including palladium-catalyzed asymmetric allylation of β-diketones, branched linker that can increase the potency of doxorubicin immunoconjugates, and diacridines that intercalate nucleic acids and inhibit DNA synthesis.
References Sawamura, M., et al.: J. Am. Chem. Soc. 114, 2586 (1997); King, H. D., et al.: Bioconjugate Chem. 10, 279 (1999); Denny, W. A., et al.: J. Med. Chem 28, 1568 (1985)

Formula: C₁₁H₁₃NO₄

Color and Shape: Neat

Molecular weight: 223.23

Ref: TR-C176180