CAS 2305-32-0

(±)-trans-1,2-Cyclohexanedicarboxylic acid

Description:

(±)-trans-1,2-Cyclohexanedicarboxylic acid, also known as trans-1,2-cyclohexanedicarboxylic acid, is a bicyclic organic compound characterized by the presence of two carboxylic acid functional groups attached to a cyclohexane ring. This compound exists as a racemic mixture, meaning it contains equal amounts of both enantiomers, which can exhibit different properties. It is typically a white crystalline solid at room temperature and is soluble in polar solvents like water and alcohols, owing to the hydrophilic nature of the carboxylic acid groups. The compound is used in various applications, including as a building block in organic synthesis and in the production of polymers. Its structural configuration contributes to its unique chemical reactivity, making it a valuable intermediate in the synthesis of more complex molecules. Additionally, (±)-trans-1,2-Cyclohexanedicarboxylic acid can participate in various chemical reactions, such as esterification and amidation, further expanding its utility in chemical research and industry.

Formula: C₈H₁₂O₄

InChI: InChI=1/C8H12O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h5-6H,1-4H2,(H,9,10)(H,11,12)/t5-,6-/s2

InChI key: InChIKey=QSAWQNUELGIYBC-IOMOGOHMNA-N

SMILES: C(O)(=O)[C@H]1[C@H](C(O)=O)CCCC1

Synonyms:

• (1R,2R)-cyclohexane-1,2-dicarboxylate
• (1R,2S)-cyclohexane-1,2-dicarboxylic acid
• (1S,2S)-cyclohexane-1,2-dicarboxylic acid
• 1,2-Cyclohexanedicarboxylic acid, (1R,2R)-rel-
• 1,2-Cyclohexanedicarboxylic acid, trans-
• Lurasidone Intermediate(1)
• NSC 31593
• Trans-1,2-Cyclohexanedicarboxylicacid
• rel-(1R,2R)-1,2-Cyclohexanedicarboxylic acid
• trans-1,2-Cyclohexanedicarboxylic acid
• trans-Hexahydrophthalic acid

trans-1,2-Cyclohexanedicarboxylic Acid

CAS: 2305-32-0

Formula: C₈H₁₂O₄

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 172.18

Ref: 3B-C0474

1,2-Cyclohexanedicarboxylic acid, (1R,2R)-rel-

CAS: 2305-32-0

Formula: C₈H₁₂O₄

Purity: 95%

Color and Shape: Liquid

Molecular weight: 172.1785

Ref: IN-DA002M0K

trans-1,2-Cyclohexanedicarboxylic Acid

CAS: 2305-32-0

trans-1,2-Cyclohexanedicarboxylic Acid

Formula: C₈H₁₂O₄

Purity: 98% Trans91%

Color and Shape: white to off white to gray solid

Molecular weight: 172.18g/mol

Ref: 54-OR350372

trans-1,2-Cyclohexanedicarboxylic acid

CAS: 2305-32-0

Formula: C₈H₁₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 172.18

Ref: 10-F050400

trans-1,2-Cyclohexanedicarboxylic Acid

Controlled Product

CAS: 2305-32-0

Applications trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.
References Dossetter, A.G., et al.: J. Med. Chem., 55, 6363 (2012); Shao, P.P., et al.: Bioorg. Med. Chem. Lett., 15, 1901 (2005)

Formula: C₈H₁₂O₄

Color and Shape: White

Molecular weight: 172.18

Ref: TR-C984565

trans-1,2-Cyclohexanedicarboxylic acid, 98%

CAS: 2305-32-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₂O₄

Purity: 98%

Molecular weight: 172.18

Ref: 02-L11288